Detalhe da pesquisa
1.
Tucidinostat plus exemestane for postmenopausal patients with advanced, hormone receptor-positive breast cancer (ACE): a randomised, double-blind, placebo-controlled, phase 3 trial.
Lancet Oncol
; 20(6): 806-815, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31036468
2.
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anticancer Drugs
; 30(9): 909-916, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30998512
3.
CS2164, a novel multi-target inhibitor against tumor angiogenesis, mitosis and chronic inflammation with anti-tumor potency.
Cancer Sci
; 108(3): 469-477, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28004478
4.
Impact of chiglitazar on glycemic control in type 2 diabetic patients with metabolic syndrome and insulin resistance: A pooled data analysis from two phase III trials.
J Diabetes
; 16(2): e13484, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853916
5.
Advances in targeting histone deacetylase for treatment of solid tumors.
J Hematol Oncol
; 17(1): 37, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38822399
6.
Analysis of blood methylation quantitative trait loci in East Asians reveals ancestry-specific impacts on complex traits.
Nat Genet
; 56(5): 846-860, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38641644
7.
Therapeutic potential of tucidinostat, a subtype-selective HDAC inhibitor, in cancer treatment.
Front Pharmacol
; 13: 932914, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36120308
8.
Application of p21 and klf2 reporter gene assays to identify selective histone deacetylase inhibitors for cancer therapy.
Bioorg Med Chem Lett
; 21(1): 110-6, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145737
9.
Chidamide and Radiotherapy Synergistically Induce Cell Apoptosis and Suppress Tumor Growth and Cancer Stemness by Regulating the MiR-375-EIF4G3 Axis in Lung Squamous Cell Carcinomas.
J Oncol
; 2021: 4936207, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34194495
10.
Efficacy and safety of chiglitazar, a novel peroxisome proliferator-activated receptor pan-agonist, in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, phase 3 trial (CMAP).
Sci Bull (Beijing)
; 66(15): 1571-1580, 2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36654286
11.
Chiglitazar monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomized, double-blind, phase 3 trial (CMAS).
Sci Bull (Beijing)
; 66(15): 1581-1590, 2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36654287
12.
Relationship between cerebral hypoxic tissue volume and prognosis after stroke.
Eur Neurol
; 63(1): 52-9, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20029217
13.
Therapeutic treatment of a novel selective JAK3/JAK1/TBK1 inhibitor, CS12192, in rat and mouse models of rheumatoid arthritis.
Int Immunopharmacol
; 77: 105914, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31634789
14.
Naringenin and hesperetin, two flavonoids derived from Citrus aurantium up-regulate transcription of adiponectin.
Phytother Res
; 22(10): 1400-3, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18690615
15.
[Preliminary study on the value of 99Tc(m)-HL91 imaging in predicting sensitivity to radiotherapy in patients with nasopharyngeal carcinoma].
Zhonghua Zhong Liu Za Zhi
; 29(5): 369-72, 2007 May.
Artigo
em Chinês
| MEDLINE | ID: mdl-17892134
16.
Chiglitazar Preferentially Regulates Gene Expression via Configuration-Restricted Binding and Phosphorylation Inhibition of PPARγ.
PPAR Res
; 2017: 4313561, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29056962
17.
Peroxisome proliferator-activated receptor-gamma transcriptionally up-regulates hormone-sensitive lipase via the involvement of specificity protein-1.
Endocrinology
; 147(2): 875-84, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16269451
18.
The PPARalpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats.
Br J Pharmacol
; 148(5): 610-8, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16751799
19.
Development of chidamide for peripheral T-cell lymphoma, the first orphan drug approved in China.
Intractable Rare Dis Res
; 5(3): 185-91, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27672541
20.
Follow-up and evaluation of the pregnancy outcome in women of reproductive age with Graves' disease after 131Iodine treatment.
J Radiat Res
; 57(6): 702-708, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27618833