Detalhe da pesquisa
1.
Peptide Stability Is Important but Not a General Requirement for Antimicrobial and Antibiofilm Activity In Vitro and In Vivo.
Mol Pharm
; 20(1): 738-749, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36485036
2.
Two distinct amphipathic peptide antibiotics with systemic efficacy.
Proc Natl Acad Sci U S A
; 117(32): 19446-19454, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32723829
3.
Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens.
Proc Natl Acad Sci U S A
; 116(27): 13517-13522, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209048
4.
Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37.
Adv Exp Med Biol
; 1117: 215-240, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30980360
5.
The π Configuration of the WWW Motif of a Short Trp-Rich Peptide Is Critical for Targeting Bacterial Membranes, Disrupting Preformed Biofilms, and Killing Methicillin-Resistant Staphylococcus aureus.
Biochemistry
; 56(31): 4039-4043, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28731688
6.
Arginine-lysine positional swap of the LL-37 peptides reveals evolutional advantages of the native sequence and leads to bacterial probes.
Biochim Biophys Acta Biomembr
; 1859(8): 1350-1361, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28450045
7.
Small molecule mimics of DFTamP1, a database designed anti-Staphylococcal peptide.
Bioorg Med Chem
; 25(3): 864-869, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28011203
8.
Decoding the functional roles of cationic side chains of the major antimicrobial region of human cathelicidin LL-37.
Antimicrob Agents Chemother
; 56(2): 845-56, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22083479
9.
Short and Robust Anti-Infective Lipopeptides Engineered Based on the Minimal Antimicrobial Peptide KR12 of Human LL-37.
ACS Infect Dis
; 7(6): 1795-1808, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33890759
10.
Sequence Permutation Generates Peptides with Different Antimicrobial and Antibiofilm Activities.
Pharmaceuticals (Basel)
; 13(10)2020 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32992772
11.
Modulation of antimicrobial potency of human cathelicidin peptides against the ESKAPE pathogens and in vivo efficacy in a murine catheter-associated biofilm model.
Biochim Biophys Acta Biomembr
; 1861(9): 1592-1602, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31319057
12.
Amino Acid Composition Determines Peptide Activity Spectrum and Hot-Spot-Based Design of Merecidin.
Adv Biosyst
; 2(5)2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30800727
13.
Antibacterial, antifungal, anticancer activities and structural bioinformatics analysis of six naturally occurring temporins.
Peptides
; 106: 9-20, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29842923
14.
Design and surface immobilization of short anti-biofilm peptides.
Acta Biomater
; 49: 316-328, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27915018
15.
Anti-Staphylococcal Biofilm Effects of Human Cathelicidin Peptides.
ACS Med Chem Lett
; 7(1): 117-21, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819677
16.
Small lipopeptides possess anti-biofilm capability comparable to daptomycin and vancomycin.
RSC Adv
; 5(73): 59758-59769, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26257894
17.
Antimicrobial peptides in 2014.
Pharmaceuticals (Basel)
; 8(1): 123-50, 2015 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25806720
18.
Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds.
ACS Chem Biol
; 9(9): 1997-2002, 2014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25061850
19.
Mdm2 promotes genetic instability and transformation independent of p53.
Mol Cell Biol
; 28(15): 4862-74, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18541670
20.
A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.
J Biol Chem
; 282(2): 1322-33, 2007 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17110379