Pesquisa | Portal de Pesquisa da BVS

1.

Control of ribosomal RNA synthesis by hematopoietic transcription factors.

Antony, Charles; George, Subin S; Blum, Justin; Somers, Patrick; Thorsheim, Chelsea L; Wu-Corts, Dexter J; Ai, Yuxi; Gao, Long; Lv, Kaosheng; Tremblay, Michel G; Moss, Tom; Tan, Kai; Wilusz, Jeremy E; Ganley, Austen R D; Pimkin, Maxim; Paralkar, Vikram R.

Mol Cell ; 82(20): 3826-3839.e9, 2022 10 20.

Artigo em Inglês | MEDLINE | ID: mdl-36113481

2.

A protein synthesis brake for hematopoietic stem cell maintenance.

Lv, Kaosheng; Tong, Wei.

Genes Dev ; 36(15-16): 871-873, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-36207141

3.

CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.

Lv, Kaosheng; Jiang, Jing; Donaghy, Ryan; Riling, Christopher R; Cheng, Ying; Chandra, Vemika; Rozenova, Krasimira; An, Wei; Mohapatra, Bhopal C; Goetz, Benjamin T; Pillai, Vinodh; Han, Xu; Todd, Emily A; Jeschke, Grace R; Langdon, Wallace Y; Kumar, Suresh; Hexner, Elizabeth O; Band, Hamid; Tong, Wei.

Genes Dev ; 31(10): 1007-1023, 2017 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-28611190

4.

Kindlin-2 controls angiogenesis through modulating Notch1 signaling.

Dong, Yuechao; Ma, Guixing; Hou, Xiaoting; Han, Yingying; Ding, Zhen; Tang, Wanze; Chen, Litong; Chen, Yangshan; Zhou, Bo; Rao, Feng; Lv, Kaosheng; Du, Changzheng; Cao, Huiling.

Cell Mol Life Sci ; 80(8): 223, 2023 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-37480504

5.

Depalmitoylation rewires FLT3-ITD signaling and exacerbates leukemia progression.

Lv, Kaosheng; Ren, Jian-Gang; Han, Xu; Gui, Jun; Gong, Chujie; Tong, Wei.

Blood ; 138(22): 2244-2255, 2021 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-34111291

6.

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination.

Donaghy, Ryan; Han, Xu; Rozenova, Krasimira; Lv, Kaosheng; Jiang, Qinqin; Doepner, Miriam; Greenberg, Roger A; Tong, Wei.

Blood ; 133(14): 1560-1571, 2019 04 04.

Artigo em Inglês | MEDLINE | ID: mdl-30755420

7.

Hidden conformational codes.

Lv, Kaosheng; Tong, Wei.

Blood ; 142(21): 1766-1768, 2023 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-37995103

8.

Waking up CML leukemia stem cells for the kill.

Lv, Kaosheng; Tong, Wei.

Blood ; 139(5): 647-648, 2022 02 03.

Artigo em Inglês | MEDLINE | ID: mdl-35113154

9.

Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.

Lv, Kaosheng; Chen, Liang; Li, Yuanjun; Li, Zenglong; Zheng, Pengli; Liu, Yingying; Chen, Jianguo; Teng, Junlin.

J Neurosci ; 35(6): 2559-71, 2015 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-25673849

10.

Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3).

Yue, Michael M; Lv, Kaosheng; Meredith, Stephen C; Martindale, Jennifer L; Gorospe, Myriam; Schuger, Lucia.

J Biol Chem ; 289(49): 33971-83, 2014 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-25336651

11.

PACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability.

Liu, Yingying; Lv, Kaosheng; Li, Zenglong; Yu, Albert C H; Chen, Jianguo; Teng, Junlin.

J Biol Chem ; 287(47): 39911-24, 2012 Nov 16.

Artigo em Inglês | MEDLINE | ID: mdl-23035120

12.

RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.

Ren, Jian-Gang; Xing, Bowen; Lv, Kaosheng; O'Keefe, Rachel A; Wu, Mengfang; Wang, Ruoxing; Bauer, Kaylyn M; Ghazaryan, Arevik; Burslem, George M; Zhang, Jing; O'Connell, Ryan M; Pillai, Vinodh; Hexner, Elizabeth O; Philips, Mark R; Tong, Wei.

J Clin Invest ; 133(12)2023 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-37317963

13.

BRAF-V600E utilizes posttranscriptional mechanisms to amplify LPS-induced TNFα production in dendritic cells in a mouse model of Langerhans cell histiocytosis.

Minichino, Danielle; Lv, Kaosheng; Chu, Niansheng; Tong, Wei; Behrens, Edward M.

J Leukoc Biol ; 112(5): 1089-1104, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-35648675

14.

Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization.

Dai, You-Wu; Ma, Jun-Kai; Jiang, Rui; Zhan, Xiao-Lin; Chen, Si-Ying; Feng, Lin-Lin; Zhang, Qi; Liang, Ting-Bo; Lv, Kaosheng; Yang, Guan-Jun; Lu, Jian-Fei; Chen, Jiong; Lu, Xin-Jiang.

Cell Rep ; 40(12): 111361, 2022 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-36130501

15.

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

Lv, Kaosheng; Gong, Chujie; Antony, Charles; Han, Xu; Ren, Jian-Gang; Donaghy, Ryan; Cheng, Ying; Pellegrino, Simone; Warren, Alan J; Paralkar, Vikram R; Tong, Wei.

Cell Stem Cell ; 28(7): 1275-1290.e9, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-33711283

16.

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions.

Xu, Longyong; Liu, Xia; Peng, Fanglue; Zhang, Weijie; Zheng, Liting; Ding, Yao; Gu, Tianpeng; Lv, Kaosheng; Wang, Jin; Ortinau, Laura; Hu, Tianyuan; Shi, Xiangguo; Shi, Guojun; Shang, Ge; Sun, Shengyi; Iwawaki, Takao; Ji, Yewei; Li, Wei; Rosen, Jeffrey M; Zhang, Xiang H-F; Park, Dongsu; Adoro, Stanley; Catic, Andre; Tong, Wei; Qi, Ling; Nakada, Daisuke; Chen, Xi.

Nat Cell Biol ; 22(10): 1162-1169, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32958856

17.

Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia.

Balcerek, Joanna; Jiang, Jing; Li, Yang; Jiang, Qinqin; Holdreith, Nicholas; Singh, Brijendra; Chandra, Vemika; Lv, Kaosheng; Ren, Jian-Gang; Rozenova, Krasimira; Li, Weihua; Greenberg, Roger A; Tong, Wei.

Nat Commun ; 9(1): 3915, 2018 09 25.

Artigo em Inglês | MEDLINE | ID: mdl-30254368

18.

USP11 regulates p53 stability by deubiquitinating p53.

Ke, Jia-ying; Dai, Cong-jie; Wu, Wen-lin; Gao, Jin-hua; Xia, Ai-juan; Liu, Guang-ping; Lv, Kao-sheng; Wu, Chun-lin.

J Zhejiang Univ Sci B ; 15(12): 1032-8, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25471832

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Control of ribosomal RNA synthesis by hematopoietic transcription factors.

A protein synthesis brake for hematopoietic stem cell maintenance.

CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.

Kindlin-2 controls angiogenesis through modulating Notch1 signaling.

Depalmitoylation rewires FLT3-ITD signaling and exacerbates leukemia progression.

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination.

Hidden conformational codes.

Waking up CML leukemia stem cells for the kill.

Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.

Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3).

PACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability.

RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.

BRAF-V600E utilizes posttranscriptional mechanisms to amplify LPS-induced TNFα production in dendritic cells in a mouse model of Langerhans cell histiocytosis.

Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization.

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions.

Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia.

USP11 regulates p53 stability by deubiquitinating p53.