RESUMO
Cells from three patients with early gonadal failure and a balanced reciprocal translocation involving the long arm of the X chromosome and an autosome were studied. Fibroblasts from a patient with a similar balanced reciprocal translocation but normal reproductive capabilities were also studied. Two of the four patients were found to have serologically detectable H-Y antigen on their cells. Since H-Y antigen has been found on the cells of other patients with X chromosome abnormalities but without a Y chromosome, it is thought that the X chromosome plays a role in the regulation of H-Y antigen expression. This study suggests that the long arm of the X chromosome may be involved but the location of a regulatory gene cannot be identified in these studies. These cases do not permit us to implicate H-Y antigen as a cause of gonadal dysgenesis and early gonadal failure in females who have structurally abnormal X chromosomes.
Assuntos
Disgenesia Gonadal/genética , Antígeno H-Y/genética , Aberrações dos Cromossomos Sexuais/genética , Células Cultivadas , Bandeamento Cromossômico , Feminino , Humanos , Cariotipagem , Pele/citologia , Translocação Genética , Cromossomo XRESUMO
Forensic nursing is one example of an innovative expansion of the role nurses will fill in the health care delivery system of the future. Because current policies of advocacy programs mandate the inclusion of criminal justice and health care providers, it is especially timely to propose that the forensic nursing specialist be placed in the trauma treatment environs to serve as a valuable link in interagency cooperation, ensuring that human needs and medicolegal interests are served. Because most emergency personnel and prehospital care providers ordinarily have only secondary interests in forensic matters, the motivated and skilled forensic nurse can serve as an invaluable resource for the criminal justice system, the hospital, and the patient.
Assuntos
Medicina Legal , Especialidades de Enfermagem/métodos , Crime , Humanos , Descrição de Cargo , Responsabilidade Legal , Modelos de Enfermagem , Avaliação em Enfermagem , Especialidades de Enfermagem/organização & administração , Estados UnidosRESUMO
Forensic nursing, as a professional discipline, originally defined its role as a medical examiner's investigator in the field of death investigation. However, with the evolution of a new area of clinical practice, the application of forensic science to nursing reveals a wider role in the investigation of crime and in the legal process. Forensic nursing, as a clinical subspecialty, fills a complementary role to clinical forensic medicine. As an emerging discipline, clinical forensic nursing recognizes that health care providers must assume a mutual responsibility with forensic scientists and the criminal justice system in concern for the survivor of violent crime and perpetrators of criminal acts. The registered nurse can be a great asset in the forensic sciences. Death has become a respectable field of inquiry, demanding answers to satisfy the public need and demand to determine the cause and manner of death. Nurses can bring empathy and compassion--as well as excellent observation, clinical, and communication skills--to death investigation.