Detalhe da pesquisa
1.
Targeting Several Biologically Reported Targets of Glioblastoma Multiforme by Assaying 2D and 3D Cultured Cells.
Cell Mol Neurobiol
; 42(6): 1909-1920, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740172
2.
Aromatic Regions Govern the Recognition of NADPH Oxidase Inhibitors as Diapocynin and its Analogues.
Arch Pharm (Weinheim)
; 350(10)2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28833480
3.
N-(2-hydroxyphenyl)-2-propylpentanamide, a valproic acid aryl derivative designed in silico with improved anti-proliferative activity in HeLa, rhabdomyosarcoma and breast cancer cells.
J Enzyme Inhib Med Chem
; 31(sup3): 140-149, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27483122
4.
The effects of (-)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER).
Pharmacol Res
; 100: 309-20, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26303816
5.
GPER binding site detection and description: A flavonoid-based docking and molecular dynamics simulations study.
J Steroid Biochem Mol Biol
; 239: 106474, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38307214
6.
In silico design and cell-based evaluation of two dual anti breast cancer compounds targeting Bcl-2 and GPER.
Sci Rep
; 13(1): 17933, 2023 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863936
7.
Modifications on the Tetrahydroquinoline Scaffold Targeting a Phenylalanine Cluster on GPER as Antiproliferative Compounds against Renal, Liver and Pancreatic Cancer Cells.
Pharmaceuticals (Basel)
; 14(1)2021 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33435260
8.
Structural insight into the binding mechanism of ATP to EGFR and L858R, and T790M and L858R/T790 mutants.
J Biomol Struct Dyn
; 37(17): 4671-4684, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30558477
9.
Structural and energetic basis for novel epicatechin derivatives acting as GPER agonists through the MMGBSA method.
J Steroid Biochem Mol Biol
; 189: 176-186, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30851383
10.
Synthesis and In Vitro Evaluation of Tetrahydroquinoline Derivatives as Antiproliferative Compounds of Breast Cancer via Targeting the GPER.
Anticancer Agents Med Chem
; 19(6): 760-771, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30451119
11.
Selection of a GPER1 Ligand via Ligand-based Virtual Screening Coupled to Molecular Dynamics Simulations and Its Anti-proliferative Effects on Breast Cancer Cells.
Anticancer Agents Med Chem
; 18(11): 1629-1638, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29745344
12.
Antiprotozoal Constituents from Annona cherimola Miller, a Plant Used in Mexican Traditional Medicine for the Treatment of Diarrhea and Dysentery.
Pharmacogn Mag
; 13(49): 148-152, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28216899
13.
Antihyperglycemic Activity of the Leaves from Annona cherimola Miller and Rutin on Alloxan-induced Diabetic Rats.
Pharmacognosy Res
; 9(1): 1-6, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250646
14.
Docking and QSAR Studies of Aryl-valproic Acid Derivatives to Identify Antiproliferative Agents Targeting the HDAC8.
Anticancer Agents Med Chem
; 17(7): 927-940, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27774878
15.
Design, in silico studies, synthesis and in vitro evaluation of oseltamivir derivatives as inhibitors of neuraminidase from influenza A virus H1N1.
Eur J Med Chem
; 128: 154-167, 2017 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28182988
16.
Understanding the molecular basis of agonist/antagonist mechanism of GPER1/GPR30 through structural and energetic analyses.
J Steroid Biochem Mol Biol
; 158: 104-116, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26772481
17.
Three amino acid derivatives of valproic acid: design, synthesis, theoretical and experimental evaluation as anticancer agents.
Anticancer Agents Med Chem
; 14(7): 984-93, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24476311