Detalhe da pesquisa
1.
RARγ activation sensitizes human myeloma cells to carfilzomib treatment through the OAS-RNase L innate immune pathway.
Blood
; 139(1): 59-72, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34411225
2.
MIF as a biomarker and therapeutic target for overcoming resistance to proteasome inhibitors in human myeloma.
Blood
; 136(22): 2557-2573, 2020 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32582913
3.
Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol.
J Lipid Res
; 59(12): 2287-2296, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30309895
4.
25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism.
J Lipid Res
; 59(3): 439-451, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29298812
5.
Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake.
J Biol Chem
; 290(36): 21788-99, 2015 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26187465
6.
Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II.
J Biol Chem
; 290(23): 14418-29, 2015 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25914138
7.
Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression.
Biochim Biophys Acta
; 1852(5): 1038-48, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25703139
8.
Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in ApoE-deficient mice.
Arterioscler Thromb Vasc Biol
; 35(4): 948-59, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25810299
9.
Inhibition of tumor growth by U0126 is associated with induction of interferon-γ production.
Int J Cancer
; 136(4): 771-83, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947959
10.
Identification of interferon-γ as a new molecular target of liver X receptor.
Biochem J
; 459(2): 345-54, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24438183
11.
DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism.
Biochim Biophys Acta
; 1831(6): 1134-45, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23466610
12.
Tamoxifen inhibits macrophage FABP4 expression through the combined effects of the GR and PPARγ pathways.
Biochem J
; 454(3): 467-77, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23805908
13.
IL-9/STAT3/fatty acid oxidation-mediated lipid peroxidation contributes to Tc9 cell longevity and enhanced antitumor activity.
J Clin Invest
; 132(7)2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192544
14.
A novel role of lysophosphatidic acid (LPA) in human myeloma resistance to proteasome inhibitors.
J Hematol Oncol
; 15(1): 55, 2022 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526043
15.
CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability.
Cell Metab
; 33(5): 1001-1012.e5, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33691090
16.
Enhanced Lipid Accumulation and Metabolism Are Required for the Differentiation and Activation of Tumor-Associated Macrophages.
Cancer Res
; 80(7): 1438-1450, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32015091
17.
Enhanced CAR-T activity against established tumors by polarizing human T cells to secrete interleukin-9.
Nat Commun
; 11(1): 5902, 2020 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33214555
18.
Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment.
Cell Metab
; 30(1): 143-156.e5, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31031094
19.
Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors.
Cancer Cell
; 33(6): 1048-1060.e7, 2018 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29894691
20.
Cholesterol negatively regulates IL-9-producing CD8+ T cell differentiation and antitumor activity.
J Exp Med
; 215(6): 1555-1569, 2018 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29743292