Detalhe da pesquisa
1.
Cartilage tissues regulate systemic aging via ectonucleotide pyrophosphatase/phosphodiesterase 1 in mice.
J Biol Chem
; 300(1): 105512, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38042486
2.
Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium.
Arch Toxicol
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753187
3.
Comparison of the pre-dilution and post-dilution methods for online hemodiafiltration.
J Artif Organs
; 27(1): 48-56, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37010653
4.
Quantitative Prediction of Intestinal Absorption of Drugs from In Vitro Study: Utilization of Differentiated Intestinal Epithelial Cells Derived from Intestinal Stem Cells at Crypts.
Drug Metab Dispos
; 51(9): 1136-1144, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142427
5.
Usefulness of Human Jejunal Spheroid-Derived Differentiated Intestinal Epithelial Cells for the Prediction of Intestinal Drug Absorption in Humans.
Drug Metab Dispos
; 50(3): 204-213, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34992074
6.
Predicting Total Drug Clearance and Volumes of Distribution Using the Machine Learning-Mediated Multimodal Method through the Imputation of Various Nonclinical Data.
J Chem Inf Model
; 62(17): 4057-4065, 2022 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993595
7.
Quantitative prediction of pharmacokinetic properties of drugs in humans: Recent advance in in vitro models to predict the impact of efflux transporters in the small intestine and blood-brain barrier.
J Pharmacol Sci
; 148(1): 142-151, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34924119
8.
Frequency of null genotypes of glutathione S-transferase M1 and T1 in Japanese patients with drug-induced liver injury.
Hepatol Res
; 52(10): 882-887, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35834381
9.
Relationships of hyperchloremia with hypertension and proteinuria in patients with chronic kidney disease.
Clin Exp Nephrol
; 26(9): 880-885, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35524894
10.
Characterization of the Human Intestinal Drug Transport with Ussing Chamber System Incorporating Freshly Isolated Human Jejunum.
Drug Metab Dispos
; 49(1): 84-93, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33087448
11.
Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel.
Drug Metab Dispos
; 48(5): 387-394, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32114508
12.
Practical Synthesis of [18F]Pitavastatin and Evaluation of Hepatobiliary Transport Activity in Rats by Positron Emission Tomography.
Mol Pharm
; 17(6): 1884-1898, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32271581
13.
High-normal albuminuria is strongly associated with incident chronic kidney disease in a nondiabetic population with normal range of albuminuria and normal kidney function.
Clin Exp Nephrol
; 24(5): 435-443, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32076888
14.
Elucidation of N 1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters.
Drug Metab Dispos
; 47(11): 1270-1280, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511257
15.
Extremely Photostable Electron-Deficient Phthalocyanines that Generate High Levels of Singlet Oxygen.
Chemistry
; 25(7): 1678-1682, 2019 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30457173
16.
Chemoselective Synthesis of Aryloxy-Substituted Phthalocyanines.
J Org Chem
; 84(21): 14306-14312, 2019 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31599149
17.
Correction to: Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers.
Pharm Res
; 36(4): 55, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30790061
18.
Accurate Estimation of In Vivo Inhibition Constants of Inhibitors and Fraction Metabolized of Substrates with Physiologically Based Pharmacokinetic Drug-Drug Interaction Models Incorporating Parent Drugs and Metabolites of Substrates with Cluster Newton Method.
Drug Metab Dispos
; 46(11): 1805-1816, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30135241
19.
Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice.
Drug Metab Dispos
; 46(5): 652-657, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29348124
20.
A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography.
Drug Metab Dispos
; 46(5): 719-728, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29555827