Detalhe da pesquisa
1.
Major ß cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.
Genes Dev
; 37(11-12): 490-504, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37364986
2.
ZFP92, a KRAB domain zinc finger protein enriched in pancreatic islets, binds to B1/Alu SINE transposable elements and regulates retroelements and genes.
PLoS Genet
; 19(5): e1010729, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155670
3.
Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice.
Proc Natl Acad Sci U S A
; 119(49): e2213628119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36442127
4.
A developmental lineage-based gene co-expression network for mouse pancreatic ß-cells reveals a role for Zfp800 in pancreas development.
Development
; 148(6)2021 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33653874
5.
Single-Cell RNA Sequencing of Sox17-Expressing Lineages Reveals Distinct Gene Regulatory Networks and Dynamic Developmental Trajectories.
Stem Cells
; 41(6): 643-657, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37085274
6.
Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.
Genes Dev
; 30(16): 1852-65, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27585590
7.
ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche.
Development
; 145(18)2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30126902
8.
The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal ß-cell maturation.
Development
; 144(2): 248-257, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27993987
9.
Transgene-associated human growth hormone expression in pancreatic ß-cells impairs identification of sex-based gene expression differences.
Am J Physiol Endocrinol Metab
; 316(2): E196-E209, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30532991
10.
Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.
Development
; 143(24): 4595-4607, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864380
11.
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
Immunity
; 32(6): 743-53, 2010 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20620941
12.
Nkx2.2 repressor complex regulates islet ß-cell specification and prevents ß-to-α-cell reprogramming.
Genes Dev
; 25(21): 2291-305, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22056672
13.
Cytosolic phosphoenolpyruvate carboxykinase as a cataplerotic pathway in the small intestine.
Am J Physiol Gastrointest Liver Physiol
; 315(2): G249-G258, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29631378
14.
BMP Antagonist Gremlin 2 Limits Inflammation After Myocardial Infarction.
Circ Res
; 119(3): 434-49, 2016 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27283840
15.
FUCCI tracking shows cell-cycle-dependent Neurog3 variation in pancreatic progenitors.
Genesis
; 55(9)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28772022
16.
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation.
EMBO J
; 32(10): 1393-408, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23584530
17.
Dominant and context-specific control of endodermal organ allocation by Ptf1a.
Development
; 141(22): 4385-94, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25371369
18.
Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.
Development
; 141(15): 2939-49, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25053427
19.
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.
Development
; 140(4): 751-64, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23325761
20.
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
PLoS Genet
; 9(1): e1003274, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382704