Detalhe da pesquisa
1.
Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures.
Cell
; 180(4): 655-665.e18, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32004463
2.
Crystal Structure of the Human Cannabinoid Receptor CB2.
Cell
; 176(3): 459-467.e13, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639103
3.
Crystal Structure of the Human Cannabinoid Receptor CB1.
Cell
; 167(3): 750-762.e14, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768894
4.
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds.
Nature
; 601(7893): 452-459, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34912117
5.
Author Correction: A new antibiotic selectively kills Gram-negative pathogens.
Nature
; 580(7802): E3, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32269338
6.
Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years.
Pharmacol Rev
; 75(5): 885-958, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37164640
7.
A new antibiotic selectively kills Gram-negative pathogens.
Nature
; 576(7787): 459-464, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31747680
8.
A Simple Chiral 1H NMR Method for the Discrimination of (R)- and (S)-Cannabichromene in Complex Natural Mixtures and Their Effects on TRPA1 Activity.
J Nat Prod
; 87(1): 77-84, 2024 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38158562
9.
Correction: Eid et al. Interference with TGFß1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. Molecules 2021, 26, 866.
Molecules
; 29(4)2024 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38398671
10.
Peripheral sensory neuron CB2 cannabinoid receptors are necessary for both CB2-mediated antinociceptive efficacy and sparing of morphine tolerance in a mouse model of anti-retroviral toxic neuropathy.
Pharmacol Res
; 187: 106560, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36417942
11.
Crystal structures of agonist-bound human cannabinoid receptor CB1.
Nature
; 547(7664): 468-471, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678776
12.
Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina.
Int J Mol Sci
; 24(21)2023 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37958673
13.
Differential Enantiomer-Specific Signaling of Cannabidiol at CB1 Receptors.
Mol Pharmacol
; 102(6): 259-268, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36153039
14.
Role of CB1 receptors in the acute regulation of small intestinal permeability: effects of high-fat diet.
Am J Physiol Gastrointest Liver Physiol
; 323(3): G219-G238, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35787179
15.
1-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1.
Biochem Biophys Res Commun
; 591: 31-36, 2022 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995983
16.
Blockade of CB1 or Activation of CB2 Cannabinoid Receptors Is Differentially Efficacious in the Treatment of the Early Pathological Events in Streptozotocin-Induced Diabetic Rats.
Int J Mol Sci
; 24(1)2022 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36613692
17.
A Genetically Encoded F-19 NMR Probe Reveals the Allosteric Modulation Mechanism of Cannabinoid Receptor 1.
J Am Chem Soc
; 143(40): 16320-16325, 2021 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34596399
18.
Oxa-adamantyl cannabinoids.
Bioorg Med Chem Lett
; 38: 127882, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33636308
19.
Interference with TGFß1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome.
Molecules
; 26(4)2021 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33562080
20.
Antiemetic Effects of Cannabinoid Agonists in Nonhuman Primates.
J Pharmacol Exp Ther
; 374(3): 462-468, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32561684