Detalhe da pesquisa
1.
Challenges and gaps in immunosafety evaluation of therapeutics: An IQ DruSafe survey.
Regul Toxicol Pharmacol
; 150: 105630, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38642729
2.
B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection.
J Virol
; 91(19)2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28701397
3.
Vaccine adjuvants alter TCR-based selection thresholds.
Immunity
; 28(5): 698-709, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18450485
4.
Antigen signal strength during priming determines effector CD4 T cell function and antigen sensitivity during influenza virus challenge.
J Immunol
; 193(6): 2812-20, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25086170
5.
A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination.
J Immunol
; 189(5): 2309-17, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22844120
6.
Cutting edge: in the absence of regulatory T cells, a unique Th cell population expands and leads to a loss of B cell anergy.
J Immunol
; 188(11): 5223-6, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22544930
7.
Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals.
MAbs
; 16(1): 2324801, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38441119
8.
Expansion of follicular helper T cells in the absence of Treg cells: implications for loss of B-cell anergy.
Eur J Immunol
; 42(10): 2597-607, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22777796
9.
Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection.
J Virol
; 86(23): 12826-37, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22993144
10.
The HLA class I immunopeptidomes of AAV capsid proteins.
Front Immunol
; 14: 1212136, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37662941
11.
Survey Outcome on Immunogenicity Risk Assessment Tools for Biotherapeutics: an Insight into Consensus on Methods, Application, and Utility in Drug Development.
AAPS J
; 25(4): 55, 2023 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37266912
12.
Development of a long-acting relaxin analogue, LY3540378, for treatment of chronic heart failure.
Br J Pharmacol
; 180(15): 1965-1980, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780899
13.
Peptide-MHC class II complex stability governs CD4 T cell clonal selection.
J Immunol
; 184(2): 573-81, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20007533
14.
The HLA class-II immunopeptidomes of AAV capsids proteins.
Front Immunol
; 13: 1067399, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36605211
15.
Antigen-driven T-cell repertoire selection during adaptive immune responses.
Immunol Cell Biol
; 89(1): 54-9, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20956989
16.
Regulation of CD4 T-cell receptor diversity by vaccine adjuvants.
Immunology
; 130(1): 16-22, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20331477
17.
Development of a FRET-Based Assay for Analysis of mAbs Internalization and Processing by Dendritic Cells in Preclinical Immunogenicity Risk Assessment.
AAPS J
; 22(3): 68, 2020 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32300899
18.
Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms.
MAbs
; 12(1): 1764829, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32370596
19.
CXCR5+PD-1+ follicular helper CD8 T cells control B cell tolerance.
Nat Commun
; 10(1): 4415, 2019 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31562329
20.
FcγRIIIa-dependent IFN-γ release in whole blood assay is predictive of therapeutic IgG1 antibodies safety.
MAbs
; 10(6): 913-921, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29953319