Detalhe da pesquisa
1.
Developing Therapies for Neurodegenerative Disorders: Insights from Protein Aggregation and Cellular Stress Responses.
Annu Rev Cell Dev Biol
; 36: 165-189, 2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33021824
2.
HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion.
EMBO J
; 42(14): e113168, 2023 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37248947
3.
Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring.
Mol Cell
; 73(3): 474-489.e5, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595434
4.
Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.
Brain
; 147(2): 649-664, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703312
5.
Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles.
Nucleic Acids Res
; 50(19): e112, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35979952
6.
Trazodone and patient outcomes in dementia-Limitations of naturalistic cohort data.
Int J Geriatr Psychiatry
; 37(8)2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921312
7.
Targeting the Unfolded Protein Response as a Disease-Modifying Pathway in Dementia.
Int J Mol Sci
; 23(4)2022 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216136
8.
Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.
PLoS Biol
; 16(4): e2003611, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29630591
9.
RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.
Nature
; 518(7538): 236-9, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25607368
10.
Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.
RNA
; 22(4): 623-35, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26857222
11.
Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.
Brain
; 140(6): 1768-1783, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28430857
12.
Sustained translational repression by eIF2α-P mediates prion neurodegeneration.
Nature
; 485(7399): 507-11, 2012 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22622579
13.
Fine-tuning PERK signaling for neuroprotection.
J Neurochem
; 142(6): 812-826, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28643372
14.
The unfolded protein response: mechanisms and therapy of neurodegeneration.
Brain
; 139(Pt 8): 2113-21, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27190028
15.
Targeting synaptic pathology with a novel affinity mass spectrometry approach.
Mol Cell Proteomics
; 13(10): 2584-92, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24973420
16.
Prions: generation and spread versus neurotoxicity.
J Biol Chem
; 289(29): 19862-8, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24860100
17.
Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory.
Neuropathol Appl Neurobiol
; 41(4): 414-27, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25556298
18.
PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.
Acta Neuropathol
; 130(5): 633-42, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26450683
19.
Reply: Trazodone to change the risk of neurodegeneration: bedside to bench.
Brain
; 140(8): e48, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28641370
20.
ASO targeting RBM3 temperature-controlled poison exon splicing prevents neurodegeneration in vivo.
EMBO Mol Med
; 15(5): e17157, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36946385