Detalhe da pesquisa
1.
Variable blood processing procedures contribute to plasma proteomic variability.
Clin Proteomics
; 18(1): 5, 2021 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33468058
2.
Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein.
PLoS Comput Biol
; 16(2): e1007684, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32058996
3.
Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation.
Mol Cell Proteomics
; 18(3): 534-545, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559323
4.
Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity.
Proc Natl Acad Sci U S A
; 112(11): E1297-306, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733881
5.
Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
Proc Natl Acad Sci U S A
; 110(36): E3445-54, 2013 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23946421
6.
Inhibitory Fc-Gamma IIb Receptor Signaling Induced by Multivalent IgG-Fc Is Dependent on Sialylation.
Cells
; 12(17)2023 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37681862
7.
Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis?
Arthritis Res Ther
; 23(1): 259, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34654463
8.
Engineered IgG1-Fc Molecules Define Valency Control of Cell Surface Fcγ Receptor Inhibition and Activation in Endosomes.
Front Immunol
; 11: 617767, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33679705
9.
M281, an Anti-FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First-in-Human Study.
Clin Pharmacol Ther
; 105(4): 1031-1039, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30402880
10.
Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor.
Arthritis Res Ther
; 21(1): 216, 2019 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647025
11.
Circulating Markers of Inflammation Persist in Children and Adults With Giant Aneurysms After Kawasaki Disease.
Circ Genom Precis Med
; 12(4): e002433, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30844302
12.
Pamapimod, a novel p38 mitogen-activated protein kinase inhibitor: preclinical analysis of efficacy and selectivity.
J Pharmacol Exp Ther
; 327(3): 610-9, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18776065
13.
Targeting JNK for therapeutic benefit: from junk to gold?
Nat Rev Drug Discov
; 2(7): 554-65, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12815381
14.
Fc-gamma receptors: Attractive targets for autoimmune drug discovery searching for intelligent therapeutic designs.
Autoimmun Rev
; 15(11): 1081-1088, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27491569
15.
Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors.
Sci Transl Med
; 8(365): 365ra158, 2016 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856797
16.
A Quantitative Microtiter Assay for Sialylated Glycoform Analyses Using Lectin Complexes.
J Biomol Screen
; 20(6): 768-78, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25851037
17.
Impact of the human genome on the discovery of immune-modulatory therapeutics.
Curr Opin Investig Drugs
; 7(5): 406-11, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16729715
18.
Screening for inhibitors of transcription factors using luciferase reporter gene expression in transfected cells.
Methods Mol Biol
; 225: 19-23, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12769470
19.
The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells.
Mol Immunol
; 46(7): 1458-66, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19181383
20.
Differential requirement for NF-kappaB-inducing kinase in the induction of NF-kappaB by IL-1beta, TNF-alpha, and Fas.
Am J Physiol Cell Physiol
; 283(1): C347-57, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12055104