Detalhe da pesquisa
1.
The Development and Characterization of an scFv-Fc Fusion-Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine Abuse.
J Pharmacol Exp Ther
; 374(1): 16-23, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32245884
2.
Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis.
Haemophilia
; 26(1): 164-172, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31797491
3.
A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection.
Infect Immun
; 87(5)2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30782860
4.
Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII.
Blood
; 127(5): 565-71, 2016 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26702064
5.
The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.
Blood
; 124(7): 1157-65, 2014 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24957146
6.
Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.
J Biol Chem
; 288(36): 25908-25914, 2013 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873930
7.
Catalytic domain modification and viral gene delivery of activated factor VII confers hemostasis at reduced expression levels and vector doses in vivo.
Blood
; 117(15): 3974-82, 2011 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325603
8.
Long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality.
J Clin Invest
; 118(5): 1825-34, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18398505
9.
Does rFVIIa work solo in hemophilia?
Blood
; 123(11): 1631-3, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24627522
10.
Successful treatment of canine hemophilia by continuous expression of canine FVIIa.
Blood
; 113(16): 3682-9, 2009 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19109232
11.
FVIII activity following FVIII protein infusion or FVIII gene transfer predicts the bleeding risk in hemophilia A rats.
J Thromb Haemost
; 18(7): 1586-1597, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32196903
12.
Gene-based FVIIa prophylaxis modulates the spontaneous bleeding phenotype of hemophilia A rats.
Blood Adv
; 3(3): 301-311, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30705032
13.
Over-expression of factor VIIa in vivo.
Thromb Res
; 122 Suppl 1: S70-2, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18691505
14.
Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse.
PLoS One
; 13(6): e0200060, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29958300
15.
Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII.
J Clin Invest
; 113(7): 1025-31, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15057309
16.
Advances in gene therapy using factor VIIa in hemophilia.
Semin Hematol
; 43(1 Suppl 1): S101-4, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16427374
17.
8(th) Symposium on Hemostasis: Translational and Basic Science Discoveries.
Thromb Res
; 141 Suppl 2: S1-3, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27207413
18.
Gene-based continuous expression of FVIIa for the treatment of hemophilia.
Front Biosci (Schol Ed)
; 4(1): 287-99, 2012 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22202061
19.
Mutation in the factor VII hepatocyte nuclear factor 4α-binding site contributes to factor VII deficiency.
Blood Coagul Fibrinolysis
; 22(7): 624-7, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21760481
20.
ARFI ultrasound monitoring of hemorrhage and hemostasis in vivo in canine von Willebrand disease and hemophilia.
Ultrasound Med Biol
; 37(12): 2126-32, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22033127