RESUMO
BACKGROUND: Operator radiation exposure is high during coronary procedures. The radial access decreases the rate of local vascular complications but increases operator radiation exposure. As the X-ray exposure is related to the distance between the operator and the radiation source, the use of an extension tube between the proximal part of the coronary catheter and the 'injection device' might decrease operator radiation exposure. AIMS: To demonstrate that the use of an extension tube during coronary procedures performed through the radial approach decreases operator radiation. METHODS: Overall, 230 patients were included consecutively and randomized to procedures performed with or without an extension tube. Radiation exposure measures were obtained using two electronic dosimeters, one under the lead apron and the other exposed on the physician's left arm. RESULTS: A non-significant trend towards lower left-arm operator exposure was noted in the extension tube group (28.7+/-31.0microSv vs 38.4+/-44.2microSv, p=0.0739). No significant difference was noted according to the type of procedure. Radiation levels were low compared with the series published previously and decreased for each operator during the study. CONCLUSION: The use of an extension tube did not reduce operator radiation exposure during procedures performed through the radial approach. However, physician awareness was increased during the study due to the use of an exposed electronic dosimeter. The use of exposed electronic dosimeters could therefore be recommended to allow operators to improve their protection techniques.
Assuntos
Angioplastia Coronária com Balão/instrumentação , Angiografia Coronária/instrumentação , Doenças Profissionais/prevenção & controle , Exposição Ocupacional , Saúde Ocupacional , Artéria Radial/diagnóstico por imagem , Lesões por Radiação/prevenção & controle , Proteção Radiológica , Radiografia Intervencionista/instrumentação , Idoso , Angioplastia Coronária com Balão/efeitos adversos , Atitude do Pessoal de Saúde , Conscientização , Angiografia Coronária/efeitos adversos , Desenho de Equipamento , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/etiologia , Estudos Prospectivos , Doses de Radiação , Lesões por Radiação/etiologia , Monitoramento de Radiação , Radiografia Intervencionista/efeitos adversos , Fatores de TempoRESUMO
AIMS: Radial artery spasm remains the major limitation of transradial approach for percutaneous coronary interventions. The aim of our study was to evaluate the efficacy of vasodilators in the prevention of radial artery spasm during percutaneous coronary interventions. METHODS AND RESULTS: 1,219 patients were consecutively randomized to receive placebo (n = 198), molsidomine 1 mg (n = 203), verapamil 2.5 mg (n = 409), 5 mg (n = 203) or verapamil 2.5 mg and molsidomine 1 mg (n = 206). All drugs were administered through the arterial sheath. The primary end point was the occurrence of a radial artery spasm defined by the operator as severe limitation of the catheter movement, with or without angiographic confirmation. Main characteristics including age, sex, wrist and arterial sheath diameters and procedure duration were identical across the groups. The rate of radial artery spasm was lowest in patients receiving verapamil and molsidomine (4.9%), compared to verapamil 2.5 mg or 5 mg (8.3 and 7.9%), or molsidomine 1 mg (13.3%); and placebo (22.2%) (P < 0.0001). CONCLUSION: Radial artery spasm during transradial percutaneous interventions was effectively prevented by the administration of vasodilators. The combination of verapamil 2.5 mg and molsidomine 1 mg provided the strongest relative risk reduction of spasm compared to placebo and should therefore be recommended during percutaneous coronary interventions through the radial approach.