Detalhe da pesquisa
1.
Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs.
Blood
; 140(11): 1291-1304, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35763665
2.
Mechanical checkpoint regulates monocyte differentiation in fibrotic niches.
Nat Mater
; 21(8): 939-950, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35817965
3.
Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets.
Haematologica
; 104(7): 1460-1472, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30655368
4.
Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders.
Haematologica
; 103(1): 148-162, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28983057
5.
A dominant-negative GFI1B mutation in the gray platelet syndrome.
N Engl J Med
; 370(3): 245-53, 2014 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24325358
6.
Busy signal: platelet-derived growth factor activation in myelofibrosis.
Haematologica
; 105(8): 1988-1990, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32739885
7.
Platelet CD34 expression and α/δ-granule abnormalities in GFI1B- and RUNX1-related familial bleeding disorders.
Blood
; 129(12): 1733-1736, 2017 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096094
8.
Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses.
Haematologica
; 104(6): e260-e264, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573501
9.
GFI1 is required for RUNX1/ETO positive acute myeloid leukemia.
Haematologica
; 103(9): e395-e399, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29674496
10.
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells.
J Innate Immun
; 15(1): 765-781, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37797588
11.
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.
Leukemia
; 37(2): 359-369, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36473980
12.
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine.
Sci Transl Med
; 14(649): eaba4380, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35704596
13.
The Molecular Genetics of Myeloproliferative Neoplasms.
Cold Spring Harb Perspect Med
; 10(2)2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548225
14.
Augmenting emergency granulopoiesis with CpG conditioned mesenchymal stromal cells in murine neutropenic sepsis.
Blood Adv
; 4(19): 4965-4979, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33049055
15.
Editorial: Transcriptional and epigenetic regulation in normal and aberrant hematopoiesis.
Front Mol Biosci
; 11: 1388983, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38545416
16.
The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy.
Blood Adv
; 2(23): 3428-3442, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30504235