1.
J Org Chem
; 83(24): 15144-15154, 2018 12 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30450907
RESUMO
The first report of the preparation of symmetric and nonsymmetric diaminotruxinic derivatives through the photoredox [2 + 2] cycloadditions of Erlenmeyer azlactones is described, affording the desired compounds in high regio- and diastereocontrol (only head-to-head coupling). Mechanistic studies by DFT suggest that the reaction proceeds through a neutral photocatalytic pathway.