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Exp Clin Transplant ; 17(1): 31-36, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-29251578

RESUMO

OBJECTIVES: Cervical cytology screening has been successful in reducing deaths from cervical cancer. We sought to determine risk factors for abnormal Pap test results in women undergoing kidney transplant evaluation. MATERILAS AND METHODS: We retrospectively examined women undergoing kidney transplant evaluations from 2008 to 2011. Patients were stratified based on normal cytology and atypical/malignant cytology. RESULTS: Of 404 patients, 293 patients (72.5%) had normal cytologic findings, whereas 111 (27.5%) had abnormal findings. On univariate logistic regression analyses, patients who had chronic kidney disease with an autoimmune cause (odds ratio = 2.71 [95% confidence interval, 1.41-5.19]; P = .003), previous renal transplants (odds ratio = 2.64 [95% confidence interval, 1.20-5.82], P = .016), or age ≤ 50 years (odds ratio = 1.68 [95% confidence interval, 1.08-2.61], P = .022) were more likely to have abnormal findings. Patients with normal and abnormal findings had similar rates of dialysis use. On multivariate logistic regression, patients who had chronic kidney disease with autoimmune causes (odds ratio = 2.48 [95% confidence interval, 1.26-4.88]; P = .008) and who had previous renal transplants (odds ratio = 2.67 [95% confidence interval, 1.20-5.95]; P = .017) were more likely to have abnormal findings. CONCLUSIONS: Previous kidney transplant, autoimmune disease, and age ≤ 50 years were associated with abnormalities on cervical cancer screening in our female group of patients. Patients with these characteristics may benefit more from routine cervical cancer screening than other patients evaluated for kidney transplant.


Assuntos
Colo do Útero/patologia , Achados Incidentais , Transplante de Rim , Insuficiência Renal Crônica/cirurgia , Neoplasias do Colo do Útero/patologia , Adulto , Fatores Etários , Doenças Autoimunes/complicações , Detecção Precoce de Câncer/métodos , Feminino , Humanos , Transplante de Rim/efeitos adversos , Pessoa de Meia-Idade , Teste de Papanicolaou , Valor Preditivo dos Testes , Insuficiência Renal Crônica/diagnóstico , Insuficiência Renal Crônica/etiologia , Reoperação , Estudos Retrospectivos , Fatores de Risco , Neoplasias do Colo do Útero/etiologia , Esfregaço Vaginal
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