1.
Scand J Immunol
; 65(5): 407-11, 2007 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17444950
RESUMO
Therapy with tumour necrosis factor-alpha (TNFalpha)-blocking agents is successful in treating inflammatory disorders, but carries an increased risk of manifest and reactivating infection with intracellular bacteria. In a mouse model of latent Salmonella typhimurium infection, neutralization of TNFalpha did not result in reactivation of infection, suggesting only a minor role for TNFalpha during latency of persistent Salmonella infection.