Detalhe da pesquisa
1.
Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry.
J Am Chem Soc
; 144(12): 5284-5294, 2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35293206
2.
Thiocoumarins: From the Synthesis to the Biological Applications.
Molecules
; 27(15)2022 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35956851
3.
Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin.
Molecules
; 27(3)2022 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164192
4.
Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors.
Bioorg Chem
; 108: 104689, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571810
5.
3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade.
Molecules
; 26(21)2021 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34771164
6.
Sequential dual site-selective protein labelling enabled by lysine modification.
Bioorg Med Chem
; 28(22): 115783, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33007561
7.
Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies.
Bioorg Chem
; 101: 103986, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32569895
8.
3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
Bioorg Chem
; 101: 103964, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32474182
9.
Synthesis, molecular docking and cholinesterase inhibitory activity of hydroxylated 2-phenylbenzofuran derivatives.
Bioorg Chem
; 84: 302-308, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30529848
10.
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation.
Angew Chem Int Ed Engl
; 58(20): 6640-6644, 2019 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30897271
11.
Chemo- and Regioselective Lysine Modification on Native Proteins.
J Am Chem Soc
; 140(11): 4004-4017, 2018 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29473744
12.
Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates.
Chemistry
; 24(47): 12250-12253, 2018 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29729206
13.
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation.
J Am Chem Soc
; 139(50): 18365-18375, 2017 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29206031
14.
New insights into highly potent tyrosinase inhibitors based on 3-heteroarylcoumarins: Anti-melanogenesis and antioxidant activities, and computational molecular modeling studies.
Bioorg Med Chem
; 25(5): 1687-1695, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28189394
15.
2-Phenylbenzofuran derivatives as butyrylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling.
Bioorg Med Chem Lett
; 26(9): 2308-13, 2016 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26995529
16.
Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold.
Bioorg Chem
; 61: 1-6, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26042529
17.
Study of coumarin-resveratrol hybrids as potent antioxidant compounds.
Molecules
; 20(2): 3290-308, 2015 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25690290
18.
Synthesis and structure-activity relationships of novel amino/nitro substituted 3-arylcoumarins as antibacterial agents.
Molecules
; 18(2): 1394-404, 2013 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23348993
19.
[(2S,3aR,6aR)-5-Oxohexa-hydro-furo[3,2-b]furan-2-yl]methyl acetate.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 5): o772, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23723916
20.
(1S,2S,5S)-2-Methyl-3-oxo-5-(prop-1-en-2-yl)cyclo-hexane-1-carbo-nitrile.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 5): o799, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23723940