[Correction of hyperkalemia with intravenous salbutamol in children with chronic renal insufficiency]. / Corrección de la hiperkalemia con salbutamol endovenoso en niños con insuficiencia renal crónica.

In order to evaluate the efficiency of albuterol sulfate (salbutamol) in lowering of potassium levels in uremic children with hyperkalemia, we intravenously administered salbutamol 30 micrograms/min (total doses 0.5 mg) to ten children with chronic renal failure (CRF) with high serum levels of potassium. Forty five minutes after administration, potassium serum levels were lower going from 6.79 +/- 0.57 mmol/L to 5.04 +/- 1.10 mmol/L; increasing levels were documented 6 hours later up to 5.76 +/- 0.66 mmol/L. Lowering in potassium serum levels was associated with disappearance of electrocardiographic manifestations of hyperkalemia. We observed moderated tachycardia in 90% of our patients and only one patient required withdrawal of this drug for high cardiac frequency rate. We conclude that salbutamol is a useful and safe choice in treatment of hyperkalemia in children with CRF.

[Gordon's syndrome. Report of a case]. / Síndrome de Gordon. Informe de un caso.

A 13 year old girl with hypertension (170/140 mmHg), hyperkalemia (7.3 mmol/L), hyperchloremic metabolic acidosis and normal glomerular filtration rate (creatinine clearance 128 mL/min/1.73 m2), had low plasmatic renin activity (0.20 ng/mL/h), the levels of plasma aldosterone was low (5.5 ng/100mL) and very low transtubular potassium concentration gradient. Other forms of the secondary hypertension were discarded. The patient was treated with salt restriction, oral salbutamol and furosemide, with satisfactory evolution. At present her blood pressure is 130/85 mmHg and potassium, plasmatic levels of 5.3 mmol/L.

[The Griscelli-Prunieras syndrome: a case report]. / Síndrome de Griscelli-Prunieras: informe de un caso.

It is presented a six-year-old girl with silvered hair syndrome, of Griscelli-Prunieras variety; hereditary sickness with regressive autosomic and distinguished by partial albinism and leukocytic alterations. She presented the acute phase of the sickness distinguished by: hepatosplenomegaly, thrombocytopenia, lymphadenopathy generalized, and systematic infection; it is corroborated how a hemophagocytic syndrome; during her evolution developed pancerebellar syndrome. By laboratory were corroborated: decrease phagocytosis, degranulation 0%, decrease of globulins gamma, neutropenia, skin test of PPD and Candidin negatives, there were not find the giant inclusions in bone marrow leukocyte and peripheric blood that are feature of Chediak-Higashi syndrome. Another alteration that was the distribution of mote of melanin on the hair that in the Griscelli-Prunieras syndrome are six times bigger in the Chediak-Higashi syndrome.