Detalhe da pesquisa
1.
Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii.
Int J Clin Oncol
; 28(5): 613-624, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961615
2.
CD44v3,8-10 is essential for Slug-dependent vimentin gene expression to acquire TGF-ß1-induced tumor cell motility.
Cancer Sci
; 113(8): 2654-2667, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35363934
3.
Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells.
Int J Mol Sci
; 19(10)2018 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30257515
4.
Improved chemoradiation treatment using trifluridine in human colorectal cancer cells in vitro.
Biochem Biophys Res Commun
; 494(1-2): 249-255, 2017 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29024630
5.
[Antitumor Molecular Mechanism of Trifluridine and Tipiracil Hydrochloride (TAS-102: TFTD)].
Gan To Kagaku Ryoho
; 43(1): 8-14, 2016 Jan.
Artigo
em Japonês
| MEDLINE | ID: mdl-26809521
6.
CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.
Genes Cells
; 17(12): 962-70, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23157317
7.
A semimechanistic population pharmacokinetic and pharmacodynamic model incorporating autoinduction for the dose justification of TAS-114.
CPT Pharmacometrics Syst Pharmacol
; 11(5): 604-615, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34951129
8.
Efficacy of Combination Chemotherapy Using a Novel Oral Chemotherapeutic Agent, FTD/TPI, with Ramucirumab Murine Version DC101 in a Mouse Syngeneic Cancer Transplantation Model.
J Clin Med
; 9(12)2020 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33333866
9.
Detection of trifluridine in tumors of patients with metastatic colorectal cancer treated with trifluridine/tipiracil.
Cancer Chemother Pharmacol
; 85(6): 1029-1038, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32322913
10.
ChIP-seq Analysis to Explore DNA Replication Profile in Trifluridine-treated Human Colorectal Cancer Cells In Vitro.
Anticancer Res
; 39(7): 3565-3570, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31262880
11.
CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure.
Sci Rep
; 9(1): 14861, 2019 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31619711
12.
Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression.
Oncotarget
; 9(17): 13438-13450, 2018 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29568368
13.
Combined efficacy and mechanism of trifluridine and SN-38 in a 5-FU-resistant human colorectal cancer cell lines.
Am J Cancer Res
; 7(12): 2577-2586, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29312810
14.
Effect of a novel oral chemotherapeutic agent containing a combination of trifluridine, tipiracil and the novel triple angiokinase inhibitor nintedanib, on human colorectal cancer xenografts.
Oncol Rep
; 36(6): 3123-3130, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27805254
15.
Prognostic impact of KRAS mutant type and MET amplification in metastatic and recurrent gastric cancer patients treated with first-line S-1 plus cisplatin chemotherapy.
Genes Cancer
; 7(1-2): 27-35, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27014419
16.
Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.
Nat Commun
; 7: 11117, 2016 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27030108
17.
The antibodies against 5-bromo-2'-deoxyuridine specifically recognize trifluridine incorporated into DNA.
Sci Rep
; 6: 25286, 2016 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27137226
18.
Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks.
Mol Cancer Ther
; 14(4): 1004-13, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25700705
19.
The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis.
Mol Cancer Ther
; 14(10): 2332-42, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26208523
20.
Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.
Am J Cancer Res
; 5(8): 2431-40, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396918