Detalhe da pesquisa
1.
Molnupiravir maintains antiviral activity against SARS-CoV-2 variants and exhibits a high barrier to the development of resistance.
Antimicrob Agents Chemother
; 68(1): e0095323, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047645
2.
SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.
PLoS Pathog
; 17(2): e1009225, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596266
3.
Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
J Med Chem
; 67(5): 3935-3958, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38365209
4.
Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates.
Proc Natl Acad Sci U S A
; 107(23): 10655-60, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20483992
5.
Antiviral activity and in vitro mutation development pathways of MK-6186, a novel nonnucleoside reverse transcriptase inhibitor.
Antimicrob Agents Chemother
; 56(6): 3324-35, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22391531
6.
Functional profiling of Covid 19 vaccine candidate by flow virometry.
Vaccine
; 40(37): 5529-5536, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35985887
7.
Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase.
Nat Commun
; 12(1): 3040, 2021 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031403
8.
Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.
ACS Med Chem Lett
; 12(1): 99-106, 2021 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33488970
9.
Distinct mutation pathways of non-subtype B HIV-1 during in vitro resistance selection with nonnucleoside reverse transcriptase inhibitors.
Antimicrob Agents Chemother
; 54(11): 4812-24, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805392
10.
The macaque gut microbiome in health, lentiviral infection, and chronic enterocolitis.
PLoS Pathog
; 4(2): e20, 2008 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18248093
11.
Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor.
Antimicrob Agents Chemother
; 53(6): 2424-31, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19289522
12.
Mechanistic Study of Common Non-Nucleoside Reverse Transcriptase Inhibitor-Resistant Mutations with K103N and Y181C Substitutions.
Viruses
; 8(10)2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27669286
13.
Recombinant rhabdoviruses as potential vaccines for HIV-1 and other diseases.
Curr HIV Res
; 1(2): 229-37, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15043205
14.
HIV-1 vaccines: the search continues.
Clin Lab Med
; 22(3): 799-820, viii, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12244598
15.
Assessment of the susceptibility of mutant HIV-1 to antiviral agents.
J Virol Methods
; 165(2): 230-7, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20153375
16.
Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rhesus macaques and protect from an AIDS-like disease.
J Infect Dis
; 195(7): 980-8, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17330788
17.
Immunogenicity of cytopathic and noncytopathic viral vectors.
J Virol
; 80(13): 6259-66, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16775313
18.
Enhanced humoral HIV-1-specific immune responses generated from recombinant rhabdoviral-based vaccine vectors co-expressing HIV-1 proteins and IL-2.
Virology
; 344(2): 363-77, 2006 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16226782
19.
Strong cellular and humoral anti-HIV Env immune responses induced by a heterologous rhabdoviral prime-boost approach.
Virology
; 331(1): 82-93, 2005 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15582655
20.
Covalently linked human immunodeficiency virus type 1 gp120/gp41 is stably anchored in rhabdovirus particles and exposes critical neutralizing epitopes.
J Virol
; 77(23): 12782-94, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14610200