Detalhe da pesquisa
1.
Selection of appropriate non-clinical animal models to ensure translatability of novel AAV-gene therapies to the clinic.
Gene Ther
; 31(1-2): 56-63, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37612361
2.
Reprogramming the mechanism of action of chlorambucil by coupling to a G-quadruplex ligand.
J Am Chem Soc
; 136(16): 5860-3, 2014 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24697838
3.
G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells.
J Am Chem Soc
; 135(26): 9640-3, 2013 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23782415
4.
G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells.
J Am Chem Soc
; 133(8): 2658-63, 2011 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21294544
5.
Mutagenicity of tamoxifen DNA adducts in human endometrial cells and in silico prediction of p53 mutation hotspots.
Nucleic Acids Res
; 36(18): 5933-45, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18805907
6.
Mutagenicity of DNA adducts derived from ethylene oxide exposure in the pSP189 shuttle vector replicated in human Ad293 cells.
Mutat Res
; 678(2): 129-37, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19477295
7.
Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS).
Nucleic Acids Res
; 34(22): e150, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17130165
8.
An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes.
Angew Chem Int Ed Engl
; 52(5): 1428-31, 2013 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23238938
9.
Genotoxicity of the benzene metabolites para-benzoquinone and hydroquinone.
Chem Biol Interact
; 153-154: 267-70, 2005 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-15935826
10.
Comparison of the mutagenic activity of the benzene metabolites, hydroquinone and para-benzoquinone in the supF forward mutation assay: a role for minor DNA adducts formed from hydroquinone in benzene mutagenicity.
Mutat Res
; 554(1-2): 387-98, 2004 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15450434
11.
Targeting a c-MYC G-quadruplex DNA with a fragment library.
Chem Commun (Camb)
; 50(14): 1704-7, 2014 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24394582
12.
Comparison of the repair of DNA damage induced by the benzene metabolites hydroquinone and p-benzoquinone: a role for hydroquinone in benzene genotoxicity.
Carcinogenesis
; 26(3): 673-80, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15618234
13.
Mutation spectra induced by alpha-acetoxytamoxifen-DNA adducts in human DNA repair proficient and deficient (xeroderma pigmentosum complementation group A) cells.
Biochemistry
; 44(22): 8198-205, 2005 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15924439
14.
Effects of the order of exposure to a binary mixture of mutagens on the induced mutation spectra in the supF gene.
Mutagenesis
; 19(2): 137-41, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14981160
15.
DNA adducts formed from 4-hydroxytamoxifen are more mutagenic than those formed by alpha-acetoxytamoxifen in a shuttle vector target gene replicated in human Ad293 cells.
Biochemistry
; 41(28): 8899-906, 2002 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12102632