Detalhe da pesquisa
1.
A mass spectrometry assay for detection of endogenous and lentiviral engineered hemoglobin in cultured cells and sickle cell disease mice.
J Gene Med
; 26(1): e3567, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37455676
2.
Fate control engagement augments NK cell responses in LV/hu-IL-12 transduced sarcoma.
Exp Mol Pathol
; 137: 104898, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38729059
3.
rAAV-mediated over-expression of acid ceramidase prevents retinopathy in a mouse model of Farber lipogranulomatosis.
Gene Ther
; 30(3-4): 297-308, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35902747
4.
Skin inflammation and impaired adipogenesis in a mouse model of acid ceramidase deficiency.
J Inherit Metab Dis
; 45(6): 1175-1190, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36083604
5.
Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target.
Proc Natl Acad Sci U S A
; 116(40): 20097-20103, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31527255
6.
Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing.
Mol Genet Metab
; 134(1-2): 117-131, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34340879
7.
Acid Ceramidase Deficiency in Mice Leads to Severe Ocular Pathology and Visual Impairment.
Am J Pathol
; 189(2): 320-338, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30472209
8.
Hepatic pathology and altered gene transcription in a murine model of acid ceramidase deficiency.
Lab Invest
; 99(10): 1572-1592, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31186526
9.
Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency.
Am J Physiol Lung Cell Mol Physiol
; 314(3): L406-L420, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29167126
10.
Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities.
Am J Pathol
; 187(4): 864-883, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28342444
11.
Corrigendum to "Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing" [2021 Sep-Oct;134(1-2):117-131].
Mol Genet Metab
; 139(1): 107541, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36849293
12.
Human mesenchymal stromal cells do not promote recurrence of soft tissue sarcomas in mouse xenografts after radiation and surgery.
Cytotherapy
; 20(8): 1001-1012, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30076069
13.
Acid Ceramidase Deficiency is characterized by a unique plasma cytokine and ceramide profile that is altered by therapy.
Biochim Biophys Acta Mol Basis Dis
; 1863(2): 386-394, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27915031
14.
Roscoe Owen Brady, MD: Remembrances of co-investigators and colleagues.
Mol Genet Metab
; 120(1-2): 1-7, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27866832
15.
Development of Novel Immunotherapies for Multiple Myeloma.
Int J Mol Sci
; 17(9)2016 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27618026
16.
On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging.
Anal Chem
; 86(16): 8303-11, 2014 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25072097
17.
Identification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer.
Mol Cell Proteomics
; 11(12): 1870-84, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22986220
18.
Roscoe Owen Brady: Passion for patients.
Proc Natl Acad Sci U S A
; 113(42): 11644-11645, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791045
19.
Adiponectin overexpression improves metabolic abnormalities caused by acid ceramidase deficiency but does not prolong lifespan in a mouse model of Farber Disease.
Mol Genet Metab Rep
; 39: 101077, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38595987
20.
Localized interleukin-12 delivery for immunotherapy of solid tumours.
J Cell Mol Med
; 17(11): 1465-74, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24251770