Detalhe da pesquisa
1.
Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. alcohol dehydrogenase toward NADH cosubstrate specificity.
Biotechnol Bioeng
; 110(11): 2803-14, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23686719
2.
The crystal structure of human α(1)-microglobulin reveals a potential haem-binding site.
Biochem J
; 445(2): 175-82, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22512701
3.
Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase.
Bioorg Med Chem
; 18(10): 3518-34, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20430628
4.
Multiple assembly states of lumazine synthase: a model relating catalytic function and molecular assembly.
J Mol Biol
; 362(4): 753-70, 2006 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16935304
5.
Cloning, purification, crystallization and preliminary crystallographic analysis of SecA from Enterococcus faecalis.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 62(Pt 6): 583-5, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16754988
6.
The structure of the N-terminal domain of riboflavin synthase in complex with riboflavin at 2.6A resolution.
J Mol Biol
; 331(5): 1053-63, 2003 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-12927541
7.
A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus.
J Mol Biol
; 328(1): 167-82, 2003 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-12684006
8.
Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthase.
J Mol Biol
; 326(3): 783-93, 2003 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12581640
9.
Formation of metal nanoclusters on specific surface sites of protein molecules.
J Mol Biol
; 321(2): 341-53, 2002 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12144790
10.
Expression, purification, crystallization and preliminary X-ray analysis of a nucleoside kinase from the hyperthermophile Methanocaldococcus jannaschii.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 61(Pt 6): 591-4, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16511104
11.
Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family.
Acta Crystallogr D Biol Crystallogr
; 62(Pt 9): 1085-97, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16929110
12.
Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.
Biochemistry
; 44(8): 2746-58, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15723519