[The "weak and sensitive elements" of the pediatric and adolescents' clinical trials]. / Los "puntos débiles o sensibles" de los Ensayos Clínicos en niñas/os y adolescentes.

The ethical review of clinical research on children and adolescents should be centered in aspects related to their condition of vulnerability, which is nurtured by biological, emotional, equity and justice elements.However, the suggested vision in this case, without overlooking previously mentioned characteristics, is the one that seeks to delve deeper in one of the actors of the research process: the clinical research protocol.The objective is to determine the presence or not of "fragile zones or weak spots" in its interior, that when individualized and considered, will contribute to improve the quality of the ethical review on children and adolescent research.