Detalhe da pesquisa
1.
Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2.
Mol Cell
; 70(3): 449-461.e5, 2018 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29727617
2.
TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection.
Mol Cell
; 61(2): 274-86, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26774283
3.
The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging.
Nucleic Acids Res
; 50(4): 2081-2095, 2022 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35150283
4.
Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence.
Nucleic Acids Res
; 50(13): 7493-7510, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35819196
5.
Human RAP1 specifically protects telomeres of senescent cells from DNA damage.
EMBO Rep
; 21(4): e49076, 2020 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32096305
6.
Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome.
Nucleic Acids Res
; 42(1): 315-27, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24057213
7.
The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres.
Nucleic Acids Res
; 40(21): 10809-20, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22989712
8.
Senescence-associated transcriptional derepression in subtelomeres is determined in a chromosome-end-specific manner.
Aging Cell
; 22(5): e13804, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36924026
9.
Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia.
Cell Stem Cell
; 30(2): 153-170.e9, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36736290
10.
Deficiency in DNA mismatch repair increases the rate of telomere shortening in normal human cells.
Hum Mutat
; 32(8): 939-46, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21538690
11.
Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline.
Nucleic Acids Res
; 37(18): 6225-38, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19656953
12.
The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin.
Life (Basel)
; 11(4)2021 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33804994
13.
Heterochromatin replication goes hand in hand with telomere protection.
Nat Struct Mol Biol
; 27(4): 313-318, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32231287
14.
The role of recombination in telomere length maintenance.
Biochem Soc Trans
; 37(Pt 3): 589-95, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19442255
15.
Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-associated PML bodies.
Int J Cancer
; 122(11): 2414-21, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18311780
16.
TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.
Nat Cell Biol
; 15(7): 818-28, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23792691
17.
Lack of TRF2 in ALT cells causes PML-dependent p53 activation and loss of telomeric DNA.
J Cell Biol
; 179(5): 855-67, 2007 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18056407