Detalhe da pesquisa
1.
Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.
Cell
; 173(4): 864-878.e29, 2018 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29681454
2.
Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.
Cell
; 155(3): 552-66, 2013 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24243015
3.
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
Nature
; 538(7623): 114-117, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27680702
4.
Synthesis and structure-activity studies of the V-ATPase inhibitor saliphenylhalamide (SaliPhe) and simplified analogs.
Bioorg Med Chem Lett
; 25(20): 4393-8, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26372654
5.
Epigenetic Repression of STING by MYC Promotes Immune Evasion and Resistance to Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer.
Cancer Immunol Res
; 10(7): 829-843, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35561311
6.
Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer.
Clin Cancer Res
; 27(15): 4379-4396, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011560
7.
A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery.
Cell Chem Biol
; 26(10): 1380-1392.e6, 2019 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31378711
8.
Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan.
Nat Commun
; 9(1): 2050, 2018 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29784984
9.
Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan.
Nat Commun
; 8(1): 2270, 2017 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29273768
10.
Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.
Cancer Discov
; 7(8): 832-851, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28455392
11.
Exploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution Interventions.
PLoS One
; 11(1): e0144970, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26788852
12.
RASSF1A inactivation unleashes a tumor suppressor/oncogene cascade with context-dependent consequences on cell cycle progression.
Mol Cell Biol
; 34(12): 2350-8, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24732797
13.
Using functional signature ontology (FUSION) to identify mechanisms of action for natural products.
Sci Signal
; 6(297): ra90, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24129700
14.
Host modulators of H1N1 cytopathogenicity.
PLoS One
; 7(8): e39284, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22876275
15.
Natural language query in the biochemistry and molecular biology domains based on cognition search™.
Summit Transl Bioinform
; 2009: 32-7, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21347167