1.
Annu Int Conf IEEE Eng Med Biol Soc
; 2012: 1206-9, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23366114
RESUMO
An electronically-controlled drug delivery system (eDDS) for the on-demand release of anti-inflammatory, anti-microbial and analgesic agents to aid in wound healing is currently under development. The loading of several drugs into conductive polymer films and their subsequent on-demand, controlled release upon application of an electrical potential to the polymer film has been demonstrated. The loading and release (active and passive) of Ibuprofen sodium salt - a negatively charged analgesic and anti-inflammatory agent - from polypyrrole films is described. Major challenges identified include precise control over drug loading and passive release from the conducting polymers in the absence of an applied potential.