Detalhe da pesquisa
1.
Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine.
Int J Mol Sci
; 21(3)2020 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31991717
2.
Astrocytes contribute to Aß-induced blood-brain barrier damage through activation of endothelial MMP9.
J Neurochem
; 142(3): 464-477, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28488764
3.
Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity.
J Nat Prod
; 78(11): 2704-11, 2015 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26517378
4.
Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation.
Mol Cell Neurosci
; 49(4): 423-9, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22402435
5.
Alzheimer's disease and neuroinflammation: will new drugs in clinical trials pave the way to a multi-target therapy?
Front Pharmacol
; 14: 1196413, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37332353
6.
Melatonin Activates Anti-Inflammatory Features in Microglia in a Multicellular Context: Evidence from Organotypic Brain Slices and HMC3 Cells.
Biomolecules
; 13(2)2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36830742
7.
Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
; 96(1): 77-91, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37742639
8.
Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against ß-amyloid toxicity.
Mol Pharmacol
; 81(1): 12-20, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21984253
9.
Decreased Astrocytic CCL2 Accounts for BAF-312 Effect on PBMCs Transendothelial Migration Through a Blood Brain Barrier in Vitro Model.
J Neuroimmune Pharmacol
; 17(3-4): 427-436, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34599741
10.
Microglia Contributes to BAF-312 Effects on Blood-Brain Barrier Stability.
Biomolecules
; 12(9)2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36139013
11.
Microglial polarization differentially affects neuronal vulnerability to the ß-amyloid protein: Modulation by melatonin.
Biochem Pharmacol
; 202: 115151, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750198
12.
Inverse correlation between the expression of AMPK/SIRT1 and NAMPT in psoriatic skin: A pilot study.
Adv Med Sci
; 67(2): 262-268, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35839539
13.
Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective.
Mol Pharmacol
; 79(3): 618-26, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21159998
14.
Molecular Aspects of Cellular Dysfunction in Alzheimer's Disease: The Need for a Holistic View of the Early Pathogenesis.
Biomolecules
; 11(12)2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34944450
15.
Protective effect of the sphingosine-1 phosphate receptor agonist siponimod on disrupted blood brain barrier function.
Biochem Pharmacol
; 186: 114465, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33577891
16.
SIRT1-Dependent Upregulation of BDNF in Human Microglia Challenged with Aß: An Early but Transient Response Rescued by Melatonin.
Biomedicines
; 9(5)2021 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923297
17.
Long-term incubation with beta-amyloid peptides impairs endothelium-dependent vasodilatation in isolated rat basilar artery.
Pharmacol Res
; 61(2): 157-61, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19782136
18.
Modulation of C6 Glioma Cell Proliferation by Ureido-Calix[8]arenes.
Pharmacology
; 86(3): 182-8, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20720453
19.
The Treatment of Impaired Wound Healing in Diabetes: Looking among Old Drugs.
Pharmaceuticals (Basel)
; 13(4)2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32244718
20.
The Ambiguous Role of Microglia in Aß Toxicity: Chances for Therapeutic Intervention.
Curr Neuropharmacol
; 18(5): 446-455, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003695