Detalhe da pesquisa
1.
Long-Lasting Nociplastic Pain Modulation by Repeated Administration of Sigma-1 Receptor Antagonist BD1063 in Fibromyalgia-like Mouse Models.
Int J Mol Sci
; 23(19)2022 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36233233
2.
EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration.
Int J Mol Sci
; 23(12)2022 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35743175
3.
Outside-in regulation of the readily releasable pool of synaptic vesicles by α2δ-1.
FASEB J
; 34(1): 1362-1377, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914622
4.
Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice.
Int J Mol Sci
; 22(13)2021 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34203381
5.
Urinary bladder sigma-1 receptors: A new target for cystitis treatment.
Pharmacol Res
; 155: 104724, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105755
6.
Sigma-1 Receptor and Pain.
Handb Exp Pharmacol
; 244: 131-161, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275913
7.
Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain.
Adv Exp Med Biol
; 964: 85-107, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28315267
8.
Effects of the selective sigma-1 receptor antagonist S1RA on formalin-induced pain behavior and neurotransmitter release in the spinal cord in rats.
J Neurochem
; 129(3): 484-94, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24384038
9.
Modulation of peripheral µ-opioid analgesia by σ1 receptors.
J Pharmacol Exp Ther
; 348(1): 32-45, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24155346
10.
S1RA, a selective sigma-1 receptor antagonist, inhibits inflammatory pain in the carrageenan and complete Freund's adjuvant models in mice.
Behav Pharmacol
; 25(3): 226-35, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24776490
11.
σ1 receptors are involved in the visceral pain induced by intracolonic administration of capsaicin in mice.
Anesthesiology
; 118(3): 691-700, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23299362
12.
Development of a Novel σ1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells.
ACS Chem Neurosci
; 14(11): 2201-2207, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191585
13.
Resilience to Pain-Related Depression in σ1 Receptor Knockout Mice Is Associated with the Reversal of Pain-Induced Brain Changes in Affect-Related Genes.
ACS Chem Neurosci
; 14(19): 3714-3725, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37738096
14.
Discovery of WLB-89462, a New Drug-like and Highly Selective σ2 Receptor Ligand with Neuroprotective Properties.
J Med Chem
; 66(17): 12499-12519, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607512
15.
Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.
Acta Pharm Sin B
; 13(1): 82-99, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36815042
16.
Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages.
Biochim Biophys Acta
; 1813(6): 1254-60, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21515313
17.
PPARß/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.
Biochim Biophys Acta
; 1811(2): 59-67, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21070867
18.
Evaluation of formalin-induced pain behavior and glutamate release in the spinal dorsal horn using in vivo microdialysis in conscious rats.
J Pharmacol Sci
; 120(2): 129-32, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22986364
19.
Long-lasting reflexive and nonreflexive pain responses in two mouse models of fibromyalgia-like condition.
Sci Rep
; 12(1): 9719, 2022 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35691979
20.
Comprehensive Preclinical Assessment of Sensory, Functional, Motivational-Affective, and Neurochemical Outcomes in Neuropathic Pain: The Case of the Sigma-1 Receptor.
ACS Pharmacol Transl Sci
; 5(4): 240-254, 2022 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35434530