Detalhe da pesquisa
1.
Mechanisms of Foreign Body Response Mitigation by Nitric Oxide Release.
Int J Mol Sci
; 23(19)2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36232937
2.
Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce.
Mol Ther
; 25(2): 512-522, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28153098
3.
Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models.
J Transl Med
; 15(1): 94, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28460646
4.
Experimental Validation of ARFI Surveillance of Subcutaneous Hemorrhage (ASSH) Using Calibrated Infusions in a Tissue-Mimicking Model and Dogs.
Ultrason Imaging
; 38(5): 346-58, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26614530
5.
The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy.
Blood
; 120(23): 4521-3, 2012 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22919027
6.
Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs.
Blood
; 119(13): 3024-30, 2012 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22246033
7.
AAV gene therapy in companion dogs with severe hemophilia: Real-world long-term data on immunogenicity, efficacy, and quality of life.
Mol Ther Methods Clin Dev
; 32(1): 101205, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38374963
8.
Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A.
Sci Transl Med
; 16(735): eadh0027, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38381848
9.
Analysis of vector genome integrations in multicentric lymphoma after AAV gene therapy in a severe hemophilia A dog.
Mol Ther Methods Clin Dev
; 31: 101159, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38094200
10.
Recombinant von Willebrand factor and tranexamic acid for heavy menstrual bleeding in patients with mild and moderate von Willebrand disease in the USA (VWDMin): a phase 3, open-label, randomised, crossover trial.
Lancet Haematol
; 10(8): e612-e623, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37385272
11.
Prolonged activity of factor IX as a monomeric Fc fusion protein.
Blood
; 115(10): 2057-64, 2010 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20056791
12.
Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy.
Blood
; 116(26): 5842-8, 2010 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20876851
13.
Efficacy and safety of long-term prophylaxis in severe hemophilia A dogs following liver gene therapy using AAV vectors.
Mol Ther
; 19(3): 442-9, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21081906
14.
Dexamethasone Transiently Enhances Transgene Expression in the Liver When Administered at Late-Phase Post Long-Term Adeno-Associated Virus Transduction.
Hum Gene Ther
; 33(3-4): 119-130, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34617445
15.
Chimeric Mice Engrafted With Canine Hepatocytes Exhibits Similar AAV Transduction Efficiency to Hemophilia B Dog.
Front Pharmacol
; 13: 815317, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35173619
16.
Recombinant canine B-domain-deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model.
Blood
; 114(20): 4562-5, 2009 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19770361
17.
Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.
Mol Ther
; 18(11): 1896-906, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20717103
18.
Combination of Nitric Oxide Release and Surface Texture for Mitigating the Foreign Body Response.
ACS Biomater Sci Eng
; 7(6): 2444-2452, 2021 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33848421
19.
Evolutionary insights into coagulation factor IX Padua and other high-specific-activity variants.
Blood Adv
; 5(5): 1324-1332, 2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33656538
20.
A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells.
Nat Biotechnol
; 39(1): 47-55, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199875