Detalhe da pesquisa
1.
Quantitative detection of hydrogen peroxide in rain, air, exhaled breath, and biological fluids by NMR spectroscopy.
Proc Natl Acad Sci U S A
; 119(8)2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165177
2.
Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.
Proc Natl Acad Sci U S A
; 119(40): e2210779119, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36161945
3.
Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
Blood
; 138(13): 1172-1181, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34197597
4.
Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
Proc Natl Acad Sci U S A
; 117(26): 15018-15027, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32527859
5.
MWC allosteric model explains unusual hemoglobin-oxygen binding curves from sickle cell drug binding.
Biophys J
; 120(12): 2543-2551, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932439
6.
Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.
Proc Natl Acad Sci U S A
; 114(5): E689-E696, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096387
7.
Synthesis of novel cyclic NGR/RGD peptide analogs via on resin click chemistry.
Bioorg Med Chem Lett
; 20(24): 7337-40, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21050757
8.
Theoretical Simulation of Red Cell Sickling Upon Deoxygenation Based on the Physical Chemistry of Sickle Hemoglobin Fiber Formation.
J Phys Chem B
; 122(49): 11579-11590, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30179501
9.
Synthesis of natural product-inspired inhibitors of Mycobacterium tuberculosis mycothiol-associated enzymes: the first inhibitors of GlcNAc-Ins deacetylase.
J Med Chem
; 50(25): 6326-36, 2007 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18020307
10.
Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.
J Med Chem
; 50(4): 713-25, 2007 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17263521
11.
Development of peptide nucleic acid probes for detection of the HER2 oncogene.
PLoS One
; 8(4): e58870, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23593123
12.
Expression profiling identifies epoxy anthraquinone derivative as a DNA topoisomerase inhibitor.
Cancer Lett
; 293(1): 124-31, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133050
13.
Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma.
Cancer Biol Ther
; 8(24): 2386-95, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19946221
14.
Design and synthesis of substrate-mimic inhibitors of mycothiol-S-conjugate amidase from Mycobacterium tuberculosis.
Bioorg Med Chem Lett
; 17(2): 444-7, 2007 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17084627
15.
Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation.
J Am Chem Soc
; 129(2): 361-70, 2007 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-17212416
16.
Synthetic macrolides that inhibit breast cancer cell migration in vitro.
J Am Chem Soc
; 129(9): 2434-5, 2007 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-17295491