Detalhe da pesquisa
1.
Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.
Proc Natl Acad Sci U S A
; 114(19): 5029-5034, 2017 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438992
2.
Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease.
J Neurochem
; 124(1): 59-68, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23083210
3.
CCR3 plays a role in murine age-related cognitive changes and T-cell infiltration into the brain.
Commun Biol
; 6(1): 292, 2023 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36934154
4.
Selective targeting of microglia by quantum dots.
J Neuroinflammation
; 9: 22, 2012 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22272874
5.
Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice.
Brain Behav
; 12(9): e2736, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35971662
6.
Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes.
J Neurochem
; 118(5): 879-90, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21534960
7.
The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement.
FASEB J
; 24(1): 58-69, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19720620
8.
Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aß/amyloid burden in a transgenic mouse model of Alzheimer's disease.
J Neuroinflammation
; 7: 57, 2010 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20920207
9.
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.
Brain Res
; 1216: 92-103, 2008 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18486110
10.
Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage.
J Mol Neurosci
; 31(2): 165-70, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17478890
11.
Chemotopic representations of aromatic odorants in the rat olfactory bulb.
J Comp Neurol
; 497(3): 350-66, 2006 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16736464
12.
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
Neuron
; 90(2): 245-60, 2016 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27041503
13.
Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
Biochem Pharmacol
; 97(4): 454-462, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26206194
14.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Nat Med
; 21(10): 1154-62, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26390242
15.
Progranulin protects against amyloid ß deposition and toxicity in Alzheimer's disease mouse models.
Nat Med
; 20(10): 1157-64, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25261995
16.
Fyn knock-down increases Aß, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice.
Neurobiol Aging
; 33(4): 825.e15-24, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21741124
17.
Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice.
Brain Res
; 1415: 96-102, 2011 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21872217
18.
ApoE mimetic peptide decreases Abeta production in vitro and in vivo.
Mol Neurodegener
; 5: 16, 2010 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20406479
19.
Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing.
J Biol Chem
; 283(10): 6288-99, 2008 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18089558
20.
BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice.
J Neurochem
; 99(6): 1555-63, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17083447