Detalhe da pesquisa
1.
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription.
Nucleic Acids Res
; 50(5): 2566-2586, 2022 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35150567
2.
Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells.
Nucleic Acids Res
; 48(2): 646-664, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31754707
3.
Changes in chromatin accessibility and transcriptional landscape induced by HDAC inhibitors in TP53 mutated patient-derived colon cancer organoids.
Biomed Pharmacother
; 173: 116374, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447451
4.
Acetylation and Phosphorylation in the Regulation of Hypoxia-Inducible Factor Activities: Additional Options to Modulate Adaptations to Changes in Oxygen Levels.
Life (Basel)
; 14(1)2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38276269
5.
HDACs and the epigenetic plasticity of cancer cells: Target the complexity.
Pharmacol Ther
; 238: 108190, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35430294
6.
Novel synthesis of 1,2-diaza-1,3-dienes with potential biological activity from cinnamic acids and diazonium salts of anilines.
RSC Adv
; 13(1): 456-463, 2022 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36605622
7.
Proteotoxic stress-induced apoptosis in cancer cells: understanding the susceptibility and enhancing the potency.
Cell Death Discov
; 8(1): 407, 2022 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36195608
8.
A regulative epigenetic circuit supervised by HDAC7 represses IGFBP6 and IGFBP7 expression to sustain mammary stemness.
Epigenomics
; 13(9): 683-698, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33878891
9.
HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers.
Genome Biol
; 22(1): 129, 2021 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33966634
10.
Enhancing Proteotoxic Stress in Leiomyosarcoma Cells Triggers Mitochondrial Dysfunctions, Cell Death, and Antitumor Activity in vivo.
Mol Cancer Ther
; 20(6): 1039-1051, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33785653
11.
HDAC7-mediated control of tumour microenvironment maintains proliferative and stemness competence of human mammary epithelial cells.
Mol Oncol
; 13(8): 1651-1668, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31081251