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Sensors (Basel) ; 24(15)2024 Aug 05.
Artigo em Inglês | MEDLINE | ID: mdl-39124105

RESUMO

This paper presents a new biosensor design based on the Kretschmann configuration, for the detection of analytes at different refractive indices. Our studied design consists of a TiO2/SiO2 bi-layer sandwiched between a BK7 prism and a bimetallic layer of Ag/Au plasmonic materials, covered by a layer of black phosphorus placed below the analyte-containing detection medium. The different layers of our structure and analyte detection were optimized using the angular interrogation method. High performance was achieved, with a sensitivity of 240 deg/RIU and a quality factor of 34.7 RIU-1. This biosensor can detect analytes with a wide refractive index range between 1.330 and 1.347, such as glucose detection in urine samples using a refractive index variation of 10-3. This capability offers a wide range of applications for biomedical and biochemical detection and selectivity.


Assuntos
Técnicas Biossensoriais , Glucose , Fósforo , Titânio , Fósforo/química , Técnicas Biossensoriais/métodos , Glucose/análise , Glucose/química , Humanos , Titânio/química , Prata/química , Ouro/química , Dióxido de Silício/química , Refratometria
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