[Oncocytic carcinoid of the lung]. / Onkotsitarnyi kartsinoid legkogo.

An observation of oncocytic carcinoid of the lung is described. The diagnosis was established by electron microscopic examinations which revealed a large number of mitochondria in cell elements of the tumor. Morphological differential diagnosis of this kind of carcinoid, particularly in the pre-operative period, is difficult because signs of oncocytic neoplasias such as large cell size, oxyphilia, and cytoplasmic granularity may be found in metastases of some kinds of cancers as well as in oncocytic adenoma of the lung.

[Adenoid cystic carcinoma (cylindroma) of the bronchi]. / Adenoid-kistoznaia kartsinoma (tsilindroma) bronkhov.

Cytological, histological, and ultrastructural examinations of 6 cases of adenoid cystic carcinoma of the bronchi were carried out. Cytological studies demonstrated cells of two types: smaller, rounded or slightly elongated cells with hyperchromic nuclei and scarce basophilic cytoplasm, and larger cells with clear nuclei and basophilic, slightly vacuolated cytoplasm. The cells are located among oxyphilic homogeneous substance. Histologically the tumour has a typical cribrose appearance owing to glandular-like and cyst-like cavities among alveolar cell aggregates embedded into intensely developed but poor in cells and somewhat hyalinized stroma. The invasive growth of the tumour with its extension into the depth of the lung on interalveolar septae, perivascular and peribronchial spaces with outgrowth of the capsule was manifest in all cases. Electron microscopic studies showed the tumour elements to be lowly differentiated epithelial cells. No ultrastructural signs of myothelium or secretory mucous activity was found. The results of these studies indicate that this tumour should be designated as adenoid cystic carcinoma but not adenoma of cylindromatous type.

[Chondromatous hamartoma of the lungs]. / Khondromatoznaia gamartoma legkikh.

A composite morphological examination of chondromatous pulmonary hamartoma showed this tumor always to contain epithelial structures determining the peculiar cytological picture in transthoracal puncture biopsy. Therefore, the diagnostic signs in cytological examinations of chondromatous hamartoma should include cluster-like accumulations of cubic epithelial cells, typical complexes of epithelial and stromal cells, while fragments of immature cartilage and mesenchyma make the picture distinctly trustworthy. The source of epithelial and cartilage elements in the punctate consists of the less compact peripheral parts of the tumor where the main portion of epithelial structures, immature cartilage tissue and mesenchyma are located. Some epithelial elements in their ultrastructural organization resemble the lining of embryonal lungs. otworthy. The source of epithelial and cartilage elements in the punctate consists of the less compact peripheral parts of the tumor where the main portion of epithelial structures, immature cartilage tissue and mesenchyma are located. Some epithelial elecments in their ultrastructural organization resemble the lining of embryonal lungs. The histogenesis of chondromatous hamartoma should apparently be associated with mesodermal and ectodermal components of the bronchial germ which explains the regular presence of the epithelium in this tumor.