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Gan To Kagaku Ryoho ; 41(2): 261-3, 2014 Feb.
Artigo em Japonês | MEDLINE | ID: mdl-24743211

RESUMO

In October 2008, a 66-year-old male patient underwent resection of the right half of the colon for ascending colon cancer. Histopathological examination revealed a tumor classification of tub2, pSE, ly1, v0, PM0, DM0, RM0, pN1(2/23), H0 , P0 , Stage III a. The patient was treated with uracil/tegafur plus Leucovorin(UFT/LV)chemotherapy after surgery. However, he developed Grade 2 liver dysfunction after completion of 1 course, so UFT/LV was discontinued. In June 2009, a rise in the carcinoembryonic antigen(CEA)level was observed, and computed tomography(CT)and positron emission tomography with 2-[fluorine-18]fluoro-2-deoxy-D-glucose(FDG-PET)showed a single enlarged lymph node, 2 cm in diameter, located around the aorta. We informed the patient of the therapeutic effect of anticancer drug treatment and surgery, risk of adverse events, and other management methods, and UFT/LV chemotherapy was selected as treatment. After 3 courses, the lymph node had completely disappeared, and UFT/LV was discontinued in April 2011, as there was no sign of recurrence. The patient remains alive and well. We report a case of para-aortic lymph node metastasis after surgery, treated with UFT/LV, which led to a complete response without major adverse events.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias do Colo/tratamento farmacológico , Idoso , Aorta/patologia , Neoplasias do Colo/patologia , Neoplasias do Colo/terapia , Humanos , Leucovorina/administração & dosagem , Metástase Linfática , Masculino , Indução de Remissão , Tegafur/administração & dosagem , Uracila/administração & dosagem
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