Detalhe da pesquisa
1.
Airway-resident T cells from unexposed individuals cross-recognize SARS-CoV-2.
Nat Immunol
; 23(9): 1324-1329, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36038709
2.
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.
Nat Immunol
; 19(12): 1299-1308, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30374129
3.
A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge.
Am J Respir Crit Care Med
; 208(8): 868-878, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37556679
4.
Human Infection Challenge with Serotype 3 Pneumococcus.
Am J Respir Crit Care Med
; 206(11): 1379-1392, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802840
5.
Thirteen-Valent Pneumococcal Conjugate Vaccine-Induced Immunoglobulin G (IgG) Responses in Serum Associated With Serotype-Specific IgG in the Lung.
J Infect Dis
; 225(9): 1626-1631, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34159375
6.
Targeted Transcriptomic Screen of Pneumococcal Genes Expressed during Murine and Human Infection.
Infect Immun
; 90(7): e0017522, 2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35674445
7.
Experimental Human Pneumococcal Colonization in Older Adults Is Feasible and Safe, Not Immunogenic.
Am J Respir Crit Care Med
; 203(5): 604-613, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32941735
8.
Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.
Am J Respir Crit Care Med
; 201(3): 335-347, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31626559
9.
Saliva Alternative to Upper Respiratory Swabs for SARS-CoV-2 Diagnosis.
Emerg Infect Dis
; 26(11): 2770-2771, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32917294
10.
Intrapulmonary Pharmacokinetics of Cefepime and Enmetazobactam in Healthy Volunteers: Towards New Treatments for Nosocomial Pneumonia.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33077666
11.
Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.
J Infect Dis
; 219(12): 1989-1993, 2019 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30690468
12.
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.
Respir Res
; 19(1): 66, 2018 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29669565
13.
Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.
Am J Respir Crit Care Med
; 194(12): 1523-1531, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27403678
14.
Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591).
BMC Pulm Med
; 17(1): 83, 2017 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28476111
15.
First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial.
Am J Respir Crit Care Med
; 192(7): 853-8, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26114410
16.
Serotype 3 Experimental Human Pneumococcal Challenge (EHPC) study protocol: dose ranging and reproducibility in a healthy volunteer population (challenge 3).
BMJ Open
; 14(1): e075948, 2024 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199622
17.
Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study.
Eur Respir J
; 52(4)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30305331
18.
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination.
Nat Commun
; 14(1): 6815, 2023 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37884506
19.
Detection of SARS-CoV-2 infection by saliva and nasopharyngeal sampling in frontline healthcare workers: An observational cohort study.
PLoS One
; 18(1): e0280908, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706119
20.
Comprehensive review of safety in Experimental Human Pneumococcal Challenge.
PLoS One
; 18(5): e0284399, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37141259