Detalhe da pesquisa
1.
Randomized Study of Rivaroxaban vs Placebo on Disease Progression and Symptoms Resolution in High-Risk Adults With Mild Coronavirus Disease 2019.
Clin Infect Dis
; 75(1): e473-e481, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34523673
2.
Pembrolizumab in patients with thymic carcinoma: a single-arm, single-centre, phase 2 study.
Lancet Oncol
; 19(3): 347-355, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29395863
3.
Simulation-guided phase 3 trial design to evaluate vaccine effectiveness to prevent Ebola virus disease infection: Statistical considerations, design rationale, and challenges.
Clin Trials
; 13(1): 57-65, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26768568
4.
Efavirenz modulation of sleep spindles and sleep spectral profile.
J Sleep Res
; 24(1): 66-73, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25113527
5.
A template for the authoring of statistical analysis plans.
Contemp Clin Trials Commun
; 34: 101100, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37388218
6.
Biomarkers predictive of response to pembrolizumab in head and neck cancer.
Cancer Med
; 12(6): 6603-6614, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36479637
7.
Evaluating correlation-based metric for surrogate marker qualification within a causal correlation framework.
Biometrics
; 68(2): 617-27, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22059475
8.
Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma.
J Immunother Cancer
; 10(2)2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217573
9.
End-point definition and trial design to advance tuberculosis vaccine development.
Eur Respir Rev
; 31(164)2022 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35675923
10.
Developing tuberculosis vaccines for people with HIV: consensus statements from an international expert panel.
Lancet HIV
; 9(11): e791-e800, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36240834
11.
Perspectives on statistical strategies for the regulatory biomarker qualification process.
Biomark Med
; 15(9): 669-684, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34037457
12.
How COVID-19 has fundamentally changed clinical research in global health.
Lancet Glob Health
; 9(5): e711-e720, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33865476
13.
Safety, tolerability, and pharmacokinetics of single- and multiple-dose administration of islatravir (MK-8591) in adults without HIV.
Clin Transl Sci
; 14(5): 1935-1944, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34463432
14.
Tolerability of two sequential electroporation treatments using MedPulser DNA delivery system (DDS) in healthy adults.
Mol Ther
; 17(5): 922-8, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19277016
15.
Nebulised surfactant for the treatment of severe COVID-19 in adults (COV-Surf): A structured summary of a study protocol for a randomized controlled trial.
Trials
; 21(1): 1014, 2020 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33302976
16.
Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition With Pembrolizumab Outcomes in Advanced Melanoma: Pooled Analysis of 3 Clinical Trials.
JAMA Oncol
; 6(8): 1256-1264, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32672795
17.
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial.
Lancet
; 372(9653): 1881-1893, 2008 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19012954
18.
Should baseline be a covariate or dependent variable in analyses of change from baseline in clinical trials?
Stat Med
; 28(20): 2509-30, 2009 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19610129
19.
The pharmacogenetics of OATP1B1 variants and their impact on the pharmacokinetics and efficacy of elbasvir/grazoprevir.
Pharmacogenomics
; 20(9): 631-641, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31250727
20.
A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma.
Nat Med
; 25(3): 454-461, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804515