Detalhe da pesquisa
1.
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Nature
; 616(7957): 563-573, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37046094
2.
The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.
Cell
; 149(3): 642-55, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22541434
3.
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Immunity
; 47(6): 1083-1099.e6, 2017 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29246442
4.
The Potency of a KRAS Silent Variant.
N Engl J Med
; 386(26): 2523-2525, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35767444
5.
Hypoxia and P1 receptor activation regulate the high-affinity concentrative adenosine transporter CNT2 in differentiated neuronal PC12 cells.
Biochem J
; 454(3): 437-45, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23819782
6.
Exploiting the therapeutic implications of KRAS inhibition on tumor immunity.
Cancer Cell
; 42(3): 338-357, 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471457
7.
CRISPR-Cas9 screening identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer.
Cancer Res
; 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38635884
8.
Facts and Hopes on RAS Inhibitors and Cancer Immunotherapy.
Clin Cancer Res
; 29(24): 5012-5020, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37581538
9.
Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α.
Sci Rep
; 13(1): 1889, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732563
10.
Aquaporin 3 (AQP3) participates in the cytotoxic response to nucleoside-derived drugs.
BMC Cancer
; 12: 434, 2012 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23017148
11.
Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers.
Sci Adv
; 8(29): eabm8780, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857848
12.
An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations.
Cancer Res
; 82(19): 3435-3448, 2022 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35930804
13.
Drugging the Undruggable: Advances on RAS Targeting in Cancer.
Genes (Basel)
; 12(6)2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34200676
14.
Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry.
Nat Commun
; 12(1): 5906, 2021 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34625563
15.
Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Sci Transl Med
; 13(602)2021 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34261798
16.
The human concentrative nucleoside transporter-3 C602R variant shows impaired sorting to lipid rafts and altered specificity for nucleoside-derived drugs.
Mol Pharmacol
; 78(2): 157-65, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20421346
17.
A splice variant of the SLC28A3 gene encodes a novel human concentrative nucleoside transporter-3 (hCNT3) protein localized in the endoplasmic reticulum.
FASEB J
; 23(1): 172-82, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18827020
18.
IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche.
Nat Commun
; 11(1): 764, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32034154
19.
Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3.
J Pharmacol Exp Ther
; 329(1): 252-61, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19141712
20.
Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer.
Sci Transl Med
; 11(510)2019 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31534020