Detalhe da pesquisa
1.
Can "Hazard-Cost-Effectiveness Analysis" improve the risk management of chemicals under REACH?
Regul Toxicol Pharmacol
; 147: 105561, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38246306
2.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Regul Toxicol Pharmacol
; 132: 105161, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508214
3.
Evaluation of the OECD QSAR toolbox automatic workflow for the prediction of the acute toxicity of organic chemicals to fathead minnow.
Regul Toxicol Pharmacol
; 122: 104893, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33587933
4.
QSAR Modeling of ToxCast Assays Relevant to the Molecular Initiating Events of AOPs Leading to Hepatic Steatosis.
J Chem Inf Model
; 58(8): 1501-1517, 2018 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29949360
5.
Adverse outcome pathways: opportunities, limitations and open questions.
Arch Toxicol
; 91(11): 3477-3505, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29051992
6.
Evaluation of QSAR models for the prediction of ames genotoxicity: a retrospective exercise on the chemical substances registered under the EU REACH regulation.
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev
; 32(3): 273-98, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25226221
7.
A physiologically based toxicokinetic model for the zebrafish Danio rerio.
Environ Sci Technol
; 48(1): 781-90, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24295030
8.
In Silico Prediction of Chemically Induced Mutagenicity: A Weight of Evidence Approach Integrating Information from QSAR Models and Read-Across Predictions.
Methods Mol Biol
; 2425: 149-183, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35188632
9.
Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.
Toxicol In Vitro
; 79: 105269, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34757180
10.
A linear model to predict chronic effects of chemicals on Daphnia magna.
Bull Environ Contam Toxicol
; 87(5): 494-8, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21909626
11.
Prediction of the Partition Coefficient between Adipose Tissue and Blood for Environmental Chemicals: From Single QSAR Models to an Integrated Approach.
Mol Inform
; 40(3): e2000072, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33135856
12.
An evaluation of the predictive ability of the QSAR software packages, DEREK, HAZARDEXPERT and TOPKAT, to describe chemically-induced skin irritation.
Altern Lab Anim
; 36(1): 15-24, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18333711
13.
In Silico Prediction of Chemically Induced Mutagenicity: How to Use QSAR Models and Interpret Their Results.
Methods Mol Biol
; 1425: 87-105, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27311463
14.
Exploring hyperthermophilic proteins under pressure: theoretical aspects and experimental findings.
Biochim Biophys Acta
; 1595(1-2): 392-6, 2002 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-11983413
15.
Rafts, little caves and large potholes: how lipid structure interacts with membrane proteins to create functionally diverse membrane environments.
Subcell Biochem
; 37: 35-118, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15376618
16.
Photolysis of estrone generates estrogenic photoproducts with higher activity than the parent compound.
Environ Sci Pollut Res Int
; 21(13): 7818-27, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24638837
17.
Modelling Structure Activity Landscapes with Cliffs: a Kernel Regression-Based Approach.
Mol Inform
; 32(7): 609-23, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27481769
18.
Applying quantitative structure-activity relationship approaches to nanotoxicology: current status and future potential.
Toxicology
; 313(1): 15-23, 2013 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23165187
19.
Prediction of dose-hepatotoxic response in humans based on toxicokinetic/toxicodynamic modeling with or without in vivo data: a case study with acetaminophen.
Toxicol Lett
; 220(1): 26-34, 2013 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23566899
20.
A Kernel-Based Method for Assessing Uncertainty on Individual QSAR Predictions.
Mol Inform
; 31(10): 741-51, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27476456