Detalhe da pesquisa
1.
Antiprotozoan lead discovery by aligning dry and wet screening: prediction, synthesis, and biological assay of novel quinoxalinones.
Bioorg Med Chem
; 22(5): 1568-85, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24513185
2.
Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: in silico, in vitro and in vivo activity studies.
Eur J Med Chem
; 43(9): 1797-807, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18192088
3.
Non-stochastic quadratic fingerprints and LDA-based QSAR models in hit and lead generation through virtual screening: theoretical and experimental assessment of a promising method for the discovery of new antimalarial compounds.
Eur J Med Chem
; 41(4): 483-93, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16545891
4.
A computer-based approach to the rational discovery of new trichomonacidal drugs by atom-type linear indices.
Curr Drug Discov Technol
; 2(4): 245-65, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16475921
5.
Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug.
Eur J Med Chem
; 58: 214-27, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23124218
6.
New ligand-based approach for the discovery of antitrypanosomal compounds.
Bioorg Med Chem Lett
; 16(7): 1898-904, 2006 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16455249
7.
Non-stochastic and stochastic linear indices of the 'molecular pseudograph's atom adjacency matrix': application to 'in silico' studies for the rational discovery of new antimalarial compounds.
Bioorg Med Chem
; 13(4): 1293-304, 2005 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15670938
8.
Ligand-based virtual screening and in silico design of new antimalarial compounds using nonstochastic and stochastic total and atom-type quadratic maps.
J Chem Inf Model
; 45(4): 1082-100, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16045304
9.
A linear discrimination analysis based virtual screening of trichomonacidal lead-like compounds: outcomes of in silico studies supported by experimental results.
Bioorg Med Chem Lett
; 15(17): 3838-43, 2005 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16005626
10.
A novel non-stochastic quadratic fingerprints-based approach for the 'in silico' discovery of new antitrypanosomal compounds.
Bioorg Med Chem
; 13(22): 6264-75, 2005 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16115770