Detalhe da pesquisa
1.
Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic ß-cell survival and function.
FASEB J
; 38(8): e23610, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38661000
2.
Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases.
Am J Hum Genet
; 106(6): 846-858, 2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32470372
3.
Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program.
Genome Res
; 20(6): 722-32, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20395405
4.
Exhaustive Variant Interaction Analysis using Multifactor Dimensionality Reduction.
Res Sq
; 2023 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37886566
5.
Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic ß-cell survival and function.
bioRxiv
; 2023 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502937
6.
Genetic regulation of RNA splicing in human pancreatic islets.
Genome Biol
; 23(1): 196, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36109769
7.
TIGER: The gene expression regulatory variation landscape of human pancreatic islets.
Cell Rep
; 37(2): 109807, 2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34644572
8.
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.
Nat Genet
; 51(7): 1137-1148, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31253982
9.
Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
Nat Commun
; 9(1): 2162, 2018 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29849136
10.
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
Nat Commun
; 9(1): 321, 2018 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358691
11.
Human Pancreatic ß Cell lncRNAs Control Cell-Specific Regulatory Networks.
Cell Metab
; 25(2): 400-411, 2017 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28041957
12.
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Diabetes
; 66(11): 2903-2914, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28838971
13.
TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.
Nat Cell Biol
; 17(5): 615-626, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25915126
14.
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.
Nat Genet
; 46(2): 136-143, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24413736
15.
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.
PLoS One
; 8(1): e55272, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23372846
16.
Human ß cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.
Cell Metab
; 16(4): 435-48, 2012 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23040067