Detalhe da pesquisa
1.
Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217618
2.
Biosynthesis of magnetosome-nanobody complex in Magnetospirillum gryphiswaldense MSR-1 and a magnetosome-nanobody-based enzyme-linked immunosorbent assay for the detection of tetrabromobisphenol A in water.
Anal Bioanal Chem
; 416(1): 141-149, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934249
3.
Mix-and-Read Nanobody-Based Sandwich Homogeneous Split-Luciferase Assay for the Rapid Detection of Human Soluble Epoxide Hydrolase.
Anal Chem
; 95(14): 6038-6045, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972550
4.
Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice.
Biochem Biophys Res Commun
; 667: 64-72, 2023 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37209564
5.
Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior.
Prostaglandins Other Lipid Mediat
; 164: 106702, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36529320
6.
Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits.
J Chem Inf Model
; 63(10): 3209-3225, 2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37141492
7.
Development of a sandwich ELISA for the specific quantitation of hemagglutinin (HA)-tagged proteins during their inducible expression in Escherichia coli.
Anal Bioanal Chem
; 415(23): 5563-5574, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37505234
8.
Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy.
J Enzyme Inhib Med Chem
; 38(1): 2274797, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37975322
9.
Aflatoxin B1 exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner.
Ecotoxicol Environ Saf
; 249: 114417, 2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36525946
10.
Adamantyl-ureas with pyrazoles substituted by fluoroalkanes as soluble epoxide hydrolase inhibitors.
J Fluor Chem
; 2662023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638129
11.
Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol Ratios as Indices of Soluble Epoxide Hydrolase Activity.
Int J Mol Sci
; 24(13)2023 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37445935
12.
Soluble Epoxide Hydrolase Contributes to Cell Senescence and ER Stress in Aging Mice Colon.
Int J Mol Sci
; 24(5)2023 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36901999
13.
The Generation of a Nanobody-Based ELISA for Human Microsomal Epoxide Hydrolase.
Int J Mol Sci
; 24(19)2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37834144
14.
Aflatoxin B1 Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity.
Int J Mol Sci
; 24(12)2023 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37373086
15.
The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms.
Prostaglandins Other Lipid Mediat
; 162: 106662, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35779854
16.
The Role of Hydrolases in Biology and Xenobiotics Metabolism.
Int J Mol Sci
; 23(9)2022 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563260
17.
Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women.
Int J Mol Sci
; 23(19)2022 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36233100
18.
Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety.
Int J Mol Sci
; 23(18)2022 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36142611
19.
A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column Derivatization-Double Precursor Ion Scanning Mass Spectrometry.
Molecules
; 27(1)2022 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35011515
20.
Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome.
Drug Metab Dispos
; 49(9): 810-821, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34234005