Estimation of Cadmium in Muscles of Five Freshwater Fish Species from Manzalah Lake, and Possible Human Risk Assessment of Fish Consumption (Egypt).

The Egyptian government devised a plan in 2016 to improve the unique ecological significance of northern lakes, which mentioned Manzalah Lake in the Egypt Vision 2030. In this regard, this study investigated cadmium (Cd) content in five freshwater fish species collected from Manzalah Lake in Egypt at 2018 by local fishermen. According to the findings, Clarias gariepinus recorded the highest concentration of Cd (1.40 ± 0.2 µg/g) and the lowest concentration was recorded in O. aureus (1.19 ± 0.2 µg/g). Cadmium contents of all species were largely above the permissible level of the Food Agricultural Organization (FAO)/World Health Organization (WHO) and Commission Regulation (EC). The estimated daily intake (EDI), the estimated weekly intake (EWI), and the percentages of provisional tolerable weekly intake (PTWI %) values for Cd in the C. gariepinus > Sarotherodon galilaeus > Tilapia zillii > Oreochromis niloticus > Oreochromis aureus which consumed by children, teenagers, and adults were much higher than the PTWI values established by FAO/WHO. In addition, C. gariepinus consumed by children showed the highest value of the target hazard quotient (THQ) (5.83 a day or 40.81 a week) while O. aureus that ingested by adults showed the lowest level (1.06 a day or 7.42a week). The target carcinogenic risk (TCR) of C. gariepinus in children had the greatest level (2.21 × 10-3 a day or 1.55 × 10-2 a week), whereas O. aureus in adults had the lowest level of TCR (4 × 10-4 a day or 2.81 × 10-3 a week). THQs values of Cd in the five studied species were found higher than one. Moreover, TCRs values of Cd in the five species were exceeded the US Environmental Protection Agency guideline USEPA permissible limits suggesting that a daily or weekly consumption of these species could lead to a high risk non-carcinogenic and carcinogenic for humans.

The health risk assessment of heavy metals to human health through the consumption of Tilapia spp and catfish caught from Lake Mariut, Egypt.

This work assesses the concentration of As, Cd, Pb, Hg, and Al in three of Tilapia species and catfish caught from Lake Mariut. As well as the human health risk and muscle biochemical composition. Besides, the antioxidant responses of different species. The average metal concentration order was Pb> As> Cd> Al> Hg. The Cd and Pb levels in all species; besides, the Hg levels in Oreochromis niloticus and Oreochromis aureus exceeded the maximum limits set by FAO, European legislation, and FAO/WHO. The human health risk was assessed using estimated dietary intakes, the target hazard quotient (THQ), and the carcinogenic risk (CR). THQAs was >1 in all examined fishes and closer to 1 in THQCd, Hg. As well, CR level for As was higher than the permissible value. Tilapia zillii showed significant decreases in carbohydrates compared to Clarias gariepinus; also, ash content compared to C. gariepinus, O. niloticus, and O. aureus. Furthermore, water content compared to O. aureus. In contrast, significant increases of SOD in O. niloticus compared to C. gariepinus. In addition, CAT and GPx in O. aureus compared to C. gariepinus. Also, GR in both O. niloticus and O. aureus compared to C. gariepinus, and GSH in all of Tilapia spp. compared to C. gariepinus. Data obtained provide evidence of health risks to the consumers. Therefore, more caution is required.

Correction to: Trace elements exposure influences proximate body composition and antioxidant enzyme activities of the species tilapia and catfish in Burullus Lake-Egypt: human risk assessment for the consumers.

The correct images of figs. 2 and 3 are presented in this paper.

Trace elements exposure influences proximate body composition and antioxidant enzyme activities of the species tilapia and catfish in Burullus Lake-Egypt: human risk assessment for the consumers.

The trace elements concentration in the fish estimates the contamination degree in the aquatic environment. These toxic trace elements are transported into the human through the consumption of polluted fish. This study estimated the effect of Cd, Hg, Pb, As, and Al on tilapia species and catfish Clarias gariepinus (six for each species of fish) inhabiting Burullus Lake-Egypt 30° 33'-31° 08' E and 30° 22'-31° 35' N. The highest Pb concentrations recorded in the muscle of C. gariepinus 2.29 ± 0.29 µg/g while S. galilaeus was estimated the lowest Hg concentration of 0.54 ± 0.02 µg/g which indicated the presence of contaminants exceeded the limits permitted by FAO/WHO and EC. The maximum mean carbohydrate, lipid, and protein recorded in O. niloticus 18.66, 16.33, and 58.16 mg/g, respectively; moisture in O. aureus 67.33%; and ash 16.41% in O. niloticus. The lowest amount of carbohydrate was recorded in the T. zillii 14.1 mg/g, lipid, and ash in C. gariepinus 11.65 mg/g and 3.375%, respectively. Protein and moisture in the S. galilaeus were 53.75 mg/g and 60.75%, respectively. The results recorded a marked insignificant (P > 0.05) decrease in CAT, GR, and GPx activity in O. niloticus. GSH and SOD activity was an insignificant (P > 0.05) decrease in C. gariepinus. The results concluded that the trace elements concentrations exceed the maximum permissible limits recommended in fish samples set by Egypt, FAO, WHO, and EC. The estimated weekly intake of all elements through consumption of studied fish species inhabiting Burullus Lake by a child (15 kg) in Egypt is well above the PTWI recommended by FAO/WHO, whereas it is well below the PTWI for human consumption by young people (40 kg) and adult person (70 kg), at least in respect of residual levels of studied elements excluding Cd and Hg. Thus, for consumer protection, these fish species are unsafe and have hazardous effects for children, and about youth and adult consumption, caution must be taken to consider individuals eating significant amounts of fish.