Detalhe da pesquisa
1.
Optimization of non-coding regions for a non-modified mRNA COVID-19 vaccine.
Nature
; 601(7893): 410-414, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34794169
2.
IABS/CEPI platform technology webinar: Is it possible to reduce the vaccine development time?
Biologicals
; 71: 55-60, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33966960
3.
Transcriptomic hepatotoxicity signature of chlorpromazine after short- and long-term exposure in primary human sandwich cultures.
Drug Metab Dispos
; 41(10): 1835-42, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23913027
4.
Assessment of Immunogenicity and Efficacy of CV0501 mRNA-Based Omicron COVID-19 Vaccination in Small Animal Models.
Vaccines (Basel)
; 11(2)2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36851196
5.
Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models.
Nat Commun
; 14(1): 816, 2023 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36781853
6.
Optimised Non-Coding Regions of mRNA SARS-CoV-2 Vaccine CV2CoV Improves Homologous and Heterologous Neutralising Antibody Responses.
Vaccines (Basel)
; 10(8)2022 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36016139
7.
A third dose of the unmodified COVID-19 mRNA vaccine CVnCoV enhances quality and quantity of immune responses.
Mol Ther Methods Clin Dev
; 27: 309-323, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36217434
8.
mRNA vaccines induce rapid antibody responses in mice.
NPJ Vaccines
; 7(1): 88, 2022 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35915094
9.
mRNA-based SARS-CoV-2 vaccine candidate CVnCoV induces high levels of virus-neutralising antibodies and mediates protection in rodents.
NPJ Vaccines
; 6(1): 57, 2021 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33863911
10.
mRNA Vaccines Induce Rapid Antibody Responses in Mice.
bioRxiv
; 2021 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34751269
11.
CVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2.
Nat Commun
; 12(1): 4048, 2021 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34193869
12.
Safety and immunogenicity of an mRNA-lipid nanoparticle vaccine candidate against SARS-CoV-2 : A phase 1 randomized clinical trial.
Wien Klin Wochenschr
; 133(17-18): 931-941, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378087
13.
Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.
Hepatology
; 49(6): 2031-43, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19274752
14.
Gene expression profiling in Ishikawa cells: a fingerprint for estrogen active compounds.
Toxicol Appl Pharmacol
; 236(1): 85-96, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19371625
15.
Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro.
Drug Metab Dispos
; 36(4): 702-14, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18216275
16.
Primary hepatocytes as a model to analyze species-specific toxicity and drug metabolism.
Expert Opin Drug Metab Toxicol
; 4(7): 855-70, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18624675
17.
Oestrogen receptors pathways to oestrogen responsive elements: the transactivation function-1 acts as the keystone of oestrogen receptor (ER)beta-mediated transcriptional repression of ERalpha.
J Steroid Biochem Mol Biol
; 104(3-5): 110-22, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17478088
18.
Effects of cell culture conditions on primary rat hepatocytes-cell morphology and differential gene expression.
Toxicology
; 218(2-3): 205-15, 2006 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16337326
19.
Human reporter gene assays: transcriptional activity of the androgen receptor is modulated by the cellular environment and promoter context.
Toxicology
; 220(2-3): 90-103, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16413649
20.
Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells.
J Steroid Biochem Mol Biol
; 94(1-3): 71-81, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15862952