Detalhe da pesquisa
1.
The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients.
Int J Mol Sci
; 22(15)2021 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34360796
2.
Aα-Val360: a marker of neutrophil elastase and COPD disease activity.
Eur Respir J
; 41(1): 31-8, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22523359
3.
Tracking Changes in Mobility Before and After the First SARS-CoV-2 Vaccination Using Global Positioning System Data in England and Wales (Virus Watch): Prospective Observational Community Cohort Study.
JMIR Public Health Surveill
; 9: e38072, 2023 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36884272
4.
The fibrinogen cleavage product Aα-Val360, a specific marker of neutrophil elastase activity in vivo.
Thorax
; 66(8): 686-91, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21617168
5.
Heterocycle-substituted proline dipeptides as potent VLA-4 antagonists.
Bioorg Med Chem Lett
; 20(3): 1173-6, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20022493
6.
Discovery of N-{N-[(3-cyanobenzene) sulfonyl]-4(R)-(3,3-difluoropiperidin-1-yl)-(l)-prolyl}-4-[(3',5'-dichloro-isonicotinoyl) amino]-(l)-phenylalanine (MK-0617), a highly potent and orally active VLA-4 antagonist.
Bioorg Med Chem Lett
; 19(19): 5803-6, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19713111
7.
A specific proteinase 3 activity footprint in α1-antitrypsin deficiency.
ERJ Open Res
; 5(3)2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31403052
8.
Constraining the amide bond in N-sulfonylated dipeptide VLA-4 antagonists.
Bioorg Med Chem Lett
; 18(5): 1688-91, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18242984
9.
The Relationship of the Fibrinogen Cleavage Biomarker Aα-Val360 With Disease Severity and Activity in α1-Antitrypsin Deficiency.
Chest
; 148(2): 382-388, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25569856
10.
Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichloroisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4.
J Med Chem
; 52(11): 3449-52, 2009 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19441819
11.
Characterization of alpha(4)beta(1) (CD49d/CD29) on equine leukocytes: potential utility of a potent alpha(4)beta(1) (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction).
Vet Immunol Immunopathol
; 130(1-2): 79-87, 2009 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19250687
12.
Highly constrained bicyclic VLA-4 antagonists.
Bioorg Med Chem Lett
; 17(3): 597-601, 2007 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17118652
13.
An innovative approach to helping international medical graduates to improve their communication and consultation skills: whose role is it?
Educ Prim Care
; 22(3): 182-5, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21640009
14.
Five minutes to find your ideal match: speed dating in Banbury.
Educ Prim Care
; 22(4): 253-4, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21781392
15.
Influence of acid surrogates toward potency of VLA-4 antagonist.
Bioorg Med Chem Lett
; 15(18): 4053-6, 2005 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16039122
16.
Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase.
Bioorg Med Chem Lett
; 15(8): 1997-2001, 2005 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15808455
17.
N-aryl 2,6-dimethoxybiphenylalanine analogues as VLA-4 antagonists.
Bioorg Med Chem Lett
; 12(5): 729-31, 2002 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-11858990
18.
Effects of VLA-4 antagonists in rat whole embryo culture.
Teratology
; 65(1): 26-37, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11835229
19.
N-isonicotinoyl-(L)-4-aminophenylalanine derivatives as tight binding VLA-4 antagonists.
Bioorg Med Chem Lett
; 13(11): 1891-5, 2003 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12749892
20.
N-(3-phenylsulfonyl-3-piperidinoyl)-phenylalanine derivatives as potent, selective VLA-4 antagonists.
Bioorg Med Chem Lett
; 13(5): 885-90, 2003 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12617914