[Rhabdomyolysis, ventricular fibrillation and respiratory insufficiency as a form of presentation of type-I renal tubular acidosis]. / Rabdomiolisis, fibrilación ventricular e insuficiencia ventilatoria como forma de presentación de una acidosis tubular renal tipo I.

The renal tubular acidosis type 1 might be laboratory findings or a group of muscular symptoms, renal complication or delayed growth. It can also be a non-frequent case of rhabdomyolysis, producing serious cardiac and respiratory complications such as those described in this case. This tubular disease can produce alteration of calcium and ionic metabolism, and stimulation of renin-angiotensin-aldosterone axis, both reversible with the correction of the systemic pH with alcalin.

[Neutrophil chemotaxis in patients with chronic active hepatitis]. / Quimiotaxis de los neutrófilos en pacientes con hepatitis crónica activa.

The serum of 18 patients diagnosed as having chronic active hepatitis (CAH) was studied in order to ascertain the neutrophil motility in healthy person serum. The chemotaxis and the chemokinesis induced by the serum of the patients were lower than those obtained using a control serum. When the control serum, activated by zymosan, was added to the patients serum a decrease of chemotaxis was observed. Contrary to this, when activated serum of patients was added to the control serum, there was no alteration of chemotaxis. We concluded that serum of patients affected by CAH have an inhibitor of the motility of neutrophils.

[IgM, IgG and IgA rheumatoid factors in rheumatoid arthritis]. / Factores reumatoides IgM, IgG e IgA en la artritis reumatoide.

The IgM, IgG and IgA rheumatoid factors (RF) were studied by ELISA in the serum of 122 patients with rheumatoid arthritis (RA) associating the Waaler-Rose test results, with the clinical and radiological aspects of the disease. 75 patients (61%) had RF IgM positive according to the Waaler-Rose test while the ELISA showed positive in 104 (85%). The RF (IgG was positive in 64 cases (52%) and RF IgA in 82 (67%). The levels of RF IgA were correlated to RF IgM levels, determined by the Waaler-Rose test (p < 0.01) and ELISA (p < 0.001), while RF IgG levels were not correlated to RF IgM or IgA. There was a significant correlation between RF IgA titles and Lansbury's index (p < 0.01), and between RF IgG and sedimentation rate (p < 0.01). In patients with extraarticular disease high levels of RF have been observed, especially RF IgM and IgA. We concluded that the ELISA technique is the preferred method to measure the RF.