Detalhe da pesquisa
1.
A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness.
Nat Immunol
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Artigo
em Inglês
| MEDLINE | ID: mdl-33958784
2.
A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.
Nature
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Artigo
em Inglês
| MEDLINE | ID: mdl-29342133
3.
Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.
Nature
; 558(7711): E4, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29769714
4.
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma.
Genome Res
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Artigo
em Inglês
| MEDLINE | ID: mdl-31249064
5.
Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations.
Blood
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Artigo
em Inglês
| MEDLINE | ID: mdl-25428216
6.
The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population.
Front Immunol
; 14: 1161901, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37600767
7.
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance.
Commun Biol
; 6(1): 765, 2023 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37479893
8.
Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.
Cancer Discov
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Artigo
em Inglês
| MEDLINE | ID: mdl-37694973
9.
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.
bioRxiv
; 2023 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37034724
10.
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.
Leukemia
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Artigo
em Inglês
| MEDLINE | ID: mdl-36720973
11.
SINGLE CELL DISSECTION OF DEVELOPMENTAL ORIGINS AND TRANSCRIPTIONAL HETEROGENEITY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA.
bioRxiv
; 2023 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106088
12.
PRMT5 regulates ATF4 transcript splicing and oxidative stress response.
Redox Biol
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Artigo
em Inglês
| MEDLINE | ID: mdl-35305370
13.
A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.
Leukemia
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Artigo
em Inglês
| MEDLINE | ID: mdl-36131042
14.
Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.
Cell Rep
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Artigo
em Inglês
| MEDLINE | ID: mdl-35263585
15.
The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.
Cell Stem Cell
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Artigo
em Inglês
| MEDLINE | ID: mdl-33242413
16.
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML.
Nat Commun
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Artigo
em Inglês
| MEDLINE | ID: mdl-33594052
17.
TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.
Cell Stem Cell
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Artigo
em Inglês
| MEDLINE | ID: mdl-34343492
18.
Mapping the cellular origin and early evolution of leukemia in Down syndrome.
Science
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Artigo
em Inglês
| MEDLINE | ID: mdl-34244384
19.
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia.
Cancer Discov
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Artigo
em Inglês
| MEDLINE | ID: mdl-34103329
20.
Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer.
Nat Commun
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Artigo
em Inglês
| MEDLINE | ID: mdl-31974375